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How to get fromDubuque to Louisvilleby car, plane, or bus

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There are 6 ways to get from Dubuque to Louisville by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Dubuque to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    6h 38m
    $100–574

  2. Drive 471.1 mi

    cheapest
    1. Drive from Dubuque to Louisvillecar car 471.1 mi
    8h 38m
    $86–125

  3. Drive, bus via Indianapolis

    1. Drive from Dubuque to Twixt Town Rd Transfercar car
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    3. Take the bus from Iowa City to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 38m

  4. Drive to The Eastern Iowa Airport, fly

    1. Drive from Dubuque to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    6h 27m
    $106–574

  5. Drive to Dane County Regional Airport-Truax Field, fly

    1. Drive from Dubuque to Madison-Airport-MSNcar car
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    6h 41m
    $128–728

  6. Drive, bus

    1. Drive from Dubuque to Twixt Town Rd Transfercar car
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    3. Take the bus from Iowa City to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Union Station to Louisville, KYbus bus
    17h 18m

Quad City International Airport (MLI) to Louisville International Airport (SDF) flights

Calendar68Weekly Planes
Duration5h 23mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Dubuque to Louisville.ExpandLaunch map view
  • Distance: 423.7 mi
  • Duration: 6h 38m

What companies run services between Dubuque, IA, USA and Louisville, KY, USA?

There is no direct connection from Dubuque to Louisville. However, you can drive to Moline-Airport-MLI airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take a vehicle from Dubuque to Louisville, KY via Twixt Town Rd Transfer, GTC Bay 5, GTC Bay 9, Iowa City, Chicago Bus Station, and Indianapolis Union Station in around 16h 38m.

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