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How to get fromDubuque to Louisvilleby car, plane, bus (Amtrak), bus, train, or bus (Flixbus, Greyhound, Amtrak)

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There are 8 ways to get from Dubuque to Louisville by car, plane, bus (Amtrak), bus, train, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Dubuque to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    6h 30m
    $115–624

  2. Drive  471.1 mi

    cheapest
    1. Drive from Dubuque to Louisvillecar car 471.1 mi
    8h 38m
    $86–125

  3. Bus

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    14h 51m
    $98–145

  4. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Indianapolistrain train
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 23m
    $208–355

  5. Drive to The Eastern Iowa Airport, fly

    1. Drive from Dubuque to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    6h 53m
    $116–674

  6. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    9h 21m
    $120–630

  7. Bus via Indianapolis

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h
    $101–165

  8. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 15m
    $171–300

Dubuque to Louisville by bus

Calendar7Weekly Buses
Duration14h 51mAverage Duration
Ticket$98Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Dubuque to Louisville.ExpandLaunch map view
  • Distance: 423.7 mi
  • Duration: 6h 30m

What companies run services between Dubuque, IA, USA and Louisville, KY, USA?

You can take a bus from Dubuque to Louisville, KY via Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 14h 51m.

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