There are 4 ways to get from Duke University Hospital to Roanoke by bus, train, bus (Greyhound, Flixbus), car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Durham to Greensboro Bus Stopbus
- Take the train from Greensboro to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
7h 25m$98–158Drive 124.8 mi
cheapest- Drive from Duke University Hospital to Roanokecar 124.8 mi
2h 53m$22–31Bus
- Take the bus from Durham to Greensboro Bus Stopbus
- Take the bus from Greensboro Bus Stop to Lynchburg Transit Centerbus
- Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus
8h 45m$44–72Train (Amtrak)
- Take the train from Durham Amtrak Station to Greensborotrain
- Take the train from Greensboro to Lynchburgtrain
- Take the train from Lynchburg to Roanoketrain
7h 39m$120–192
Duke University Hospital to Roanoke by foot, bus, and train
Comparing Your Travel Options
The cheapest way to get from Duke University Hospital to Roanoke is to drive which costs $21 - $35 and takes 2h 53m.
The fastest way to get from Duke University Hospital to Roanoke is to drive which takes 2h 53m and costs $21 - $35.
No, there is no direct bus from Duke University Hospital to Roanoke. However, there are services departing from Erwin Rd at Fulton St and arriving at Roanoke Bus Stop via Durham, Greensboro Bus Stop and Lynchburg Transit Center. The journey, including transfers, takes approximately 8h 45m.
No, there is no direct train from Duke University Hospital station to Roanoke. However, there are services departing from Durham Amtrak Station and arriving at Roanoke via Greensboro and Lynchburg. The journey, including transfers, takes approximately 7h 39m.
The distance between Duke University Hospital and Roanoke is 220 miles. The road distance is 125.5 miles.
The best way to get from Duke University Hospital to Roanoke without a car is to bus and train which takes 7h 25m and costs $95 - $160.
It takes approximately 7h 25m to get from Duke University Hospital to Roanoke, including transfers.
Duke University Hospital to Roanoke bus services, operated by Greyhound USA, depart from Durham station.
Duke University Hospital to Roanoke train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Duke University Hospital to Roanoke is to bus which takes 8h 45m and costs $40 - $75. Alternatively, you can train, which costs $120 - $200 and takes 7h 39m.
What companies run services between Duke University Hospital, NC, USA and Roanoke, VA, USA?
You can take a vehicle from Duke University Hospital to Roanoke Bus Stop via Erwin Rd at Fulton St, Durham Station, Durham, Greensboro Bus Stop, and Lynchburg Transit Center in around 8h 45m. Alternatively, you can take a vehicle from Duke University Hospital to Roanoke via Erwin Rd at Fulton St, Durham Station, Durham Amtrak Station, Greensboro, and Lynchburg in around 7h 39m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Lynchburg
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Amtrak
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Greensboro to Lynchburg
- Ave. Duration
- 2h 8m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Amtrak
Train from Lynchburg to Roanoke
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Lynchburg Transit Center to Roanoke Bus Stop
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- $9–15
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Bus from Greensboro Bus Stop to Lynchburg Transit Center
- Ave. Duration
- 3h 35m
- Frequency
- 4 times a week
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
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Booking & Getting There
Duke University Hospital to Roanoke bus services, operated by Greyhound USA, arrive at Greensboro Bus Stop station.
Duke University Hospital to Roanoke train services, operated by Amtrak, arrive at Greensboro station.
Yes, the driving distance between Duke University Hospital to Roanoke is 125 miles. It takes approximately 2h 53m to drive from Duke University Hospital to Roanoke.
There are 95+ hotels available in Roanoke.








