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How to get fromDuke University Hospital to Spartanburgby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, or train

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There are 5 ways to get from Duke University Hospital to Spartanburg by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train Piedmont / ...
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train Crescent
    6h 18m
    $72–158

  2. Drive 209.2 mi

    cheapest
    1. Drive from Duke University Hospital to Spartanburgcar car 209.2 mi
    3h 38m
    $39–56

  3. Bus

    1. Take the bus from Durham to Spartanburgbus bus Greyhound US0670
    6h 47m
    $54–92

  4. Fly

    1. Fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP)plane plane RDU - GSP
    6h 20m
    $402–628

  5. Bus, train

    1. Take the bus from Columbia & Rosemary to Greensboro Depotbus bus 4
    2. Take the train from Greensboro to Spartanburg Stationtrain train Crescent
    7h 55m
    $60–126

Duke University Hospital to Spartanburg by foot, bus, and train (Amtrak)

Calendar7Weekly Services
Duration6h 18mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Duke University Hospital to Spartanburg.ExpandLaunch map view
  • Distance: 225.4 mi
  • Duration: 6h 18m

What companies run services between Duke University Hospital, NC, USA and Spartanburg, SC, USA?

You can take a vehicle from Duke University Hospital to Spartanburg Station via Erwin Rd at Fulton St, Durham Station, Durham Amtrak Station, and Charlotte Amtrak Station in around 6h 18m. Alternatively, Greyhound USA operates a bus from Durham to Spartanburg twice daily. Tickets cost $35–70 and the journey takes 5h 20m. Flixbus USA also services this route once daily.

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