There are 6 ways to get from Duke University to Charleston by train (Amtrak), bus (Greyhound), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Durham Amtrak Station to Selma Stationtrain Carolinian
- Take the train from Selma Station to Charleston Amtrak Stationtrain Palmetto
8h 19m$182–292Drive 261 mi
cheapest- Drive from Duke University to Charlestoncar 261 mi
5h 46m$47–67Bus (Greyhound)
- Take the bus from Raleigh Bus Station to Charleston Bus Stationbus Greyhound US0645S
11h 47m$63–102Fly from Raleigh-Durham International Airport
- Fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS)plane RDU - CHS
7h 37m$277–489Train to Piedmont Triad International Airport, fly
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)plane GSO - CHS
8h 22m$118–463Train to Charlotte Douglas International Airport, fly
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane CLT - CHS
8h 40m$139–499
Duke University to Charleston by foot and bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Duke University to Charleston is to drive which costs $45 - $70 and takes 5h 46m.
The fastest way to get from Duke University to Charleston is to drive which takes 5h 46m and costs $45 - $70.
No, there is no direct bus from Duke University to Charleston. However, there are services departing from Flowers Dr at Duke Gardens and arriving at Transit Mall via Durham, Raleigh Bus Station, North Charleston Transit Center and Rivers Ave / Cosgrove Ave. The journey, including transfers, takes approximately 11h 47m.
No, there is no direct train from Duke University station to Charleston station. However, there are services departing from Durham Amtrak Station and arriving at Charleston Amtrak Station via Selma Station. The journey, including transfers, takes approximately 8h 19m.
The distance between Duke University and Charleston is 294 miles. The road distance is 262.5 miles.
The best way to get from Duke University to Charleston without a car is to train which takes 8h 19m and costs $180 - $300.
It takes approximately 8h 19m to get from Duke University to Charleston, including transfers.
Duke University to Charleston bus services, operated by Greyhound USA, depart from Raleigh Bus Station.
Duke University to Charleston train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Duke University to Charleston is to train which takes 8h 19m and costs $180 - $300. Alternatively, you can bus, which costs $60 - $110 and takes 11h 47m, you could also fly, which costs $270 - $490 and takes 7h 37m.
What companies run services between Duke University, NC, USA and Charleston, SC, USA?
You can take a vehicle from Duke University to Charleston via Erwin Rd at Fulton St, Durham Station, Durham Amtrak Station, Selma Station, and Charleston Amtrak Station in around 8h 19m. Alternatively, Greyhound USA operates a bus from Raleigh Bus Station to Charleston Bus Station once daily. Tickets cost $55–90 and the journey takes 7h 5m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $60–400
Flights from Piedmont Triad International Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $55–370
Flights from Piedmont Triad International Airport to Charleston International Airport via Philadelphia
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $100–500
Flights from Piedmont Triad International Airport to Charleston International Airport via Reagan Washington
- Ave. Duration
- 6h 59m
- When
- Every day
- Estimated price
- $85–460
Flights from Charlotte Douglas International Airport to Charleston International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $50–360
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $80–470
Flights from Piedmont Triad International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $75–430
Flights from Piedmont Triad International Airport to Charleston International Airport via Detroit
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $110–550
- Website
- united.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $85–480
Flights from Piedmont Triad International Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $80–460
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 4h 55m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–490
Flights from Raleigh-Durham International Airport to Charleston International Airport via Nashville
- Ave. Duration
- 6h
- When
- Tuesday and Wednesday
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Selma Station
- Ave. Duration
- 1h 19m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
Train from Selma Station to Charleston Amtrak Station
- Ave. Duration
- 4h 18m
- Frequency
- Once daily
- Estimated price
- $120–200
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $80–130
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Raleigh Bus Station to Charleston Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Duke University to Charleston bus services, operated by Greyhound USA, arrive at Charleston Bus Station.
Duke University to Charleston train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Duke University to Charleston is 263 miles. It takes approximately 5h 46m to drive from Duke University to Charleston.
There are 53+ hotels available in Charleston.







