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How to get fromDuke University to Louisvilleby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, or car

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There are 7 ways to get from Duke University to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    5h 30m
    $96–560

  2. Bus

    cheapest
    1. Take the bus from Columbia & Rosemary to Coble Transportation Centerbus bus 4
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    20h 31m
    $64–158

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    17h 54m
    $129–229

  4. Train, bus (Amtrak)

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    26h 33m
    $295–606

  5. Drive 495.9 mi

    1. Drive from Duke University to Louisvillecar car 495.9 mi
    9h 27m
    $91–131

  6. Train to Piedmont Triad International Airport, fly

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane plane GSO - SDF
    8h 12m
    $149–734

  7. Train, bus via Arlington (Amtrak)

    1. Take the train from Durham Amtrak Station to Alexandriatrain train
    2. Take the train from Alexandria to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    30h 13m
    $353–736

Duke University to Louisville by foot, bus, and subway

Calendar5Weekly Services
Duration17h 54mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Duke University to Louisville.ExpandLaunch map view
  • Distance: 440.5 mi
  • Duration: 5h 30m

What companies run services between Duke University, NC, USA and Louisville, KY, USA?

You can take a vehicle from Duke University to Louisville, KY via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 17h 54m.

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Train operators
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