There are 7 ways to get from Duke University to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Raleigh-Durham International Airport, fly
best- Take the bus from Durham Station to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane RDU - SDF
5h 40m$106–660Drive 495.9 mi
cheapest- Drive from Duke University to Louisvillecar 495.9 mi
9h 30m$91–131Bus via Atlanta
- Take the bus from Durham to Atlanta Downtownbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
17h 54m$124–209Train, bus (Amtrak)
- Take the train from Durham Amtrak Station to Greensborotrain
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
26h 3m$478–796Train to Piedmont Triad International Airport, fly
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane GSO - SDF
8h 22m$182–844Bus
- Take the bus from Columbia & Rosemary to Greensboro Depotbus 4
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
23h 18m$104–200Train, bus via Arlington (Amtrak)
- Take the train from Durham Amtrak Station to Alexandriatrain
- Take the train from Alexandria to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
29h 43m$583–926
Duke University to Louisville by foot, bus, and subway
Comparing Your Travel Options
The cheapest way to get from Duke University to Louisville is to drive which costs $90 - $140 and takes 9h 30m.
The fastest way to get from Duke University to Louisville is to bus and fly which takes 5h 40m and costs $100 - $700.
No, there is no direct bus from Duke University to Louisville. However, there are services departing from Flowers Dr at Duke Gardens and arriving at Louisville, KY via Durham, Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 17h 54m.
The distance between Duke University and Louisville is 443 miles. The road distance is 498.7 miles.
The best way to get from Duke University to Louisville without a car is to bus via Atlanta which takes 17h 54m and costs $120 - $210.
It takes approximately 5h 40m to get from Duke University to Louisville, including transfers.
Duke University to Louisville bus services, operated by Flixbus USA, depart from Durham station.
Duke University to Louisville bus services, operated by Flixbus USA, arrive at Atlanta Downtown station.
Yes, the driving distance between Duke University to Louisville is 499 miles. It takes approximately 9h 30m to drive from Duke University to Louisville.
There are 562+ hotels available in Louisville.
What companies run services between Duke University, NC, USA and Louisville, KY, USA?
You can take a vehicle from Duke University to Louisville, KY via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Nashville in around 17h 54m.
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $130–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $150–850
Flights from Piedmont Triad International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 7h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–650
Flights from Piedmont Triad International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $120–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $180–950
Flights from Piedmont Triad International Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 4h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–900
Flights from Piedmont Triad International Airport to Louisville International Airport via Philadelphia
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $190–1,000
- Website
- united.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 7m
- When
- Saturday
- Estimated price
- $130–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $160–900
Flights from Piedmont Triad International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $180–950
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 6m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Raleigh-Durham International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $120–700
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Louisville International Airport
- Ave. Duration
- 1h 41m
- When
- Wednesday and Saturday
- Estimated price
- $230–1,600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Amtrak
Train from Durham Amtrak Station to Alexandria
- Ave. Duration
- 6h 33m
- Frequency
- Once daily
- Estimated price
- $170–280
- Website
- Amtrak
Train from Alexandria to Indianapolis
- Ave. Duration
- 17h 56m
- Frequency
- 3 times a week
- Estimated price
- $390–600
- Website
- Amtrak
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Schedules at
- godurhamtransit.org
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 30m
- Frequency
- 4 times a week
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Columbus to Indianapolis Union Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 336-662-0002
- Website
- partnc.org
Bus from Columbia & Rosemary to Greensboro Depot
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $3
- Website
- http://www.partnc.org
- Schedules at
- https://www.partnc.org/27/Routes-Schedules
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Greensboro to Winston-Salem
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $6–9
- Schedules at
- Sunway Charters
- Passenger
- $6–9
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
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