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How to get fromDuke University to Louisvilleby bus, plane, bus (Flixbus, Greyhound), train, or car

Find Transport to Louisville

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There are 7 ways to get from Duke University to Louisville by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    5h 40m
    $106–660

  2. Bus

    cheapest
    1. Take the bus from Columbia & Rosemary to Greensboro Depotbus bus 4
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Louisvillebus bus
    20h 33m
    $72–164

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
    18h 9m
    $119–199

  4. Train, bus

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    26h 7m
    $228–532

  5. Drive  495.9 mi

    1. Drive from Duke University to Louisvillecar car 495.9 mi
    9h 27m
    $91–131

  6. Train to Piedmont Triad International Airport, fly

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane plane GSO - SDF
    8h 24m
    $156–779

  7. Bus, train

    1. Take the bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform Abus bus Drx
    2. Take the train from Raleigh Union Station to Toledotrain train
    3. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus
    28h 59m
    $258–558

Duke University to Louisville by foot, bus, and subway

Calendar4Weekly Services
Duration18h 9mAverage Duration
Ticket$119Cheapest Price
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Comparing Your Travel Options

Map of how to get from Duke University to Louisville.ExpandLaunch map view
  • Distance: 440.5 mi
  • Duration: 5h 40m

What companies run services between Duke University, NC, USA and Louisville, KY, USA?

You can take a vehicle from Duke University to Louisville Bus Station via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 18h 9m.

Airlines
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Bus operators

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