There are 6 ways to get from Duke University to Louisville by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Raleigh-Durham International Airport, fly
best- Take the bus from Durham Station to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane RDU - SDF
5h 40m$116–710Drive 495.8 mi
cheapest- Drive from Duke University to Louisvillecar 495.8 mi
9h 33m$85–123Bus via Atlanta
- Take the bus from Durham to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
18h 15m$126–231Bus, train
- Take the bus from Durham to Greensboro Bus Stopbus
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
25h 50m$456–761Bus to Piedmont Triad International Airport, fly
- Take the bus from Durham to Greensboro Bus Stopbus
- Fly from Piedmont Triad International Airport (GSO) to Louisville International Airport (SDF)plane GSO - SDF
8h 11m$140–709Bus
- Take the bus from Durham to Greensboro Bus Stopbus
- Take the bus from Greensboro to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
22h 7m$107–210
Duke University to Louisville by foot and bus
Comparing Your Travel Options
The cheapest way to get from Duke University to Louisville is to drive which costs $80 - $130 and takes 9h 33m.
The fastest way to get from Duke University to Louisville is to bus and fly which takes 5h 40m and costs $110 - $750.
No, there is no direct bus from Duke University to Louisville. However, there are services departing from Flowers Dr at Duke Gardens and arriving at Louisville, KY via Durham, Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 18h 15m.
The distance between Duke University and Louisville is 443 miles. The road distance is 498.7 miles.
The best way to get from Duke University to Louisville without a car is to bus via Atlanta which takes 18h 15m and costs $120 - $240.
It takes approximately 5h 40m to get from Duke University to Louisville, including transfers.
Duke University to Louisville bus services, operated by Flixbus USA, depart from Durham station.
Duke University to Louisville bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Duke University to Louisville is 499 miles. It takes approximately 9h 33m to drive from Duke University to Louisville.
There are 610+ hotels available in Louisville.
What companies run services between Duke University, NC, USA and Louisville, KY, USA?
You can take a vehicle from Duke University to Louisville, KY via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Bus Station, and Nashville in around 18h 15m.
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $140–800
Flights from Piedmont Triad International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $130–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 9m
- When
- Monday to Saturday
- Estimated price
- $140–800
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $110–700
Flights from Piedmont Triad International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $100–650
Flights from Piedmont Triad International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $150–800
Flights from Piedmont Triad International Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $140–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Philadelphia
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $160–850
- Website
- united.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Saturday and Sunday
- Estimated price
- $140–800
Flights from Piedmont Triad International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $130–750
Flights from Piedmont Triad International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $150–800
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Louisville International Airport
- Ave. Duration
- 1h 41m
- When
- Wednesday and Saturday
- Estimated price
- $280–1,700
- Website
- allegiantair.com
Flights from Piedmont Triad International Airport to Louisville International Airport via St. Petersburg
- Ave. Duration
- 6h 16m
- When
- Friday
- Estimated price
- $200–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Amtrak
Train from Charlottesville to Indianapolis
- Ave. Duration
- 15h 23m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Schedules at
- godurhamtransit.org
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Every 4 hours
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- 5 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Durham to Greensboro Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Columbus to Indianapolis Union Station
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $30–50
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Greensboro to Winston-Salem
- Ave. Duration
- 35 min
- Frequency
- Twice daily
- Estimated price
- $6–9
- Schedules at
- Sunway Charters
- Passenger
- $6–9
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
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