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How to get fromDuke University to St. Louisby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 6 ways to get from Duke University to St. Louis by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 6 bus, bus to Raleigh-Durham International Airport, fly

    best
    1. Take the bus from Flowers Dr at Duke Gardens to Durham Stationbus bus
    2. Take the bus from Durham Station to Regional Transit Centerbus bus
    3. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    5h 30m
    $558–1,110

  2. Bus

    cheapest
    1. Take the bus from Durham to Atlanta Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    21h 34m
    $126–261

  3. Bus via Atlanta

    1. Take the bus from Durham to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    20h 39m
    $129–239

  4. Bus, train

    1. Take the bus from Chapel Dr at Duke University Rd to Union Station - Bus Platform Abus bus Drx
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    32h 32m
    $358–822

  5. Drive  754.3 mi

    1. Drive from Duke University to St. Louiscar car 754.3 mi
    13h 42m
    $138–199

  6. Train to Piedmont Triad International Airport, fly

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    8h 13m
    $168–779

Duke University to St. Louis by foot, bus, and subway

Calendar4Weekly Services
Duration20h 39mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Duke University to St. Louis.ExpandLaunch map view
  • Distance: 698.8 mi
  • Duration: 5h 30m

What companies run services between Duke University, NC, USA and St. Louis, MO, USA?

You can take a vehicle from Duke University to St Louis Bus Station via Flowers Dr at Duke Gardens, Durham Station, Durham, Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 20h 39m.

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