There are 5 ways to get from Duluth to Mayo Clinic by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Duluth to St. Paulbus Jefferson Lines 912 / ...
- Take the bus from St. Paul to Rochesterbus Jefferson Lines 965
4h 48m$72–100Drive 226.2 mi
cheapest- Drive from Duluth to Mayo Cliniccar 226.2 mi
3h 50m$42–60Fly to Rochester
- Fly from Duluth International Airport (DLH) to Rochester (RST)plane DLH - RST
6h 4m$42–342Bus via Richfield
- Take the bus from Landline - Duluth Int'l Airport to Landline - MSP Terminal-2 Humphreybus Landline to MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus Groome Transportation
7h 16m$91–112Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Duluth International Airport (DLH) to Minneapolis–Saint Paul International Airport (MSP)plane DLH - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 31m$98–414
Duluth to Mayo Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Duluth to Mayo Clinic is to drive which costs $40 - $60 and takes 3h 50m.
The fastest way to get from Duluth to Mayo Clinic is to drive which takes 3h 50m and costs $40 - $60.
No, there is no direct bus from Duluth to Mayo Clinic. However, there are services departing from Duluth and arriving at Rochester via St. Paul. The journey, including transfers, takes approximately 4h 48m.
The distance between Duluth and Mayo Clinic is 229 miles. The road distance is 227.5 miles.
The best way to get from Duluth to Mayo Clinic without a car is to bus which takes 4h 48m and costs $70 - $100.
It takes approximately 4h 48m to get from Duluth to Mayo Clinic, including transfers.
Duluth to Mayo Clinic bus services, operated by Jefferson Lines, depart from Duluth station.
The best way to get from Duluth to Mayo Clinic is to bus which takes 4h 48m and costs $70 - $100. Alternatively, you can fly, which costs $40 - $350 and takes 6h 4m.
Duluth to Mayo Clinic bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Duluth to Mayo Clinic is 228 miles. It takes approximately 3h 50m to drive from Duluth to Mayo Clinic.
What companies run services between Duluth, MN, USA and Mayo Clinic, MN, USA?
You can take a bus from Duluth to Mayo Clinic via St. Paul and Rochester in around 4h 48m. Alternatively, Delta, United Airlines, and American Airlines fly from Duluth International Airport (DLH) to Rochester (RST) every 4 hours.
- Website
- delta.com
Flights from Duluth International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $40–300
Flights from Duluth International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $45–360
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Duluth to St. Paul
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $40–60
- Book at
- Jefferson Lines
- Adult
- $40–60
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
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Booking & Getting There
There are 78+ hotels available in Mayo Clinic.