Rome2Rio

How to get fromDurham to Chicagoby train, plane, train (Amtrak), bus (Flixbus), car, or bus

Find Transport to Chicago

See all options

There are 10 ways to get from Durham to Chicago by train, plane, train (Amtrak), bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly to Chicago Midway International Airport

    best
    1. Take the train from Durham Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane plane BOS - MDW
    6h 11m
    $107–446

  2. Train (Amtrak)

    1. Take the train from Durham Station to Bostontrain train Downeaster
    2. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    24h 51m
    $353–743

  3. Bus

    1. Take the bus from Portsmouth Bus Stop to New York Midtownbus bus FlixBus N2615
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2641 / ...
    26h 48m
    $189–325

  4. Drive 986.3 mi

    1. Drive from Durham to Chicagocar car 986.3 mi
    18h 6m
    $180–260

  5. Train to Boston Logan Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Durham Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane plane BOS - ORD
    6h 36m
    $627–946

  6. Train to Portland, fly to Chicago Midway International Airport

    1. Take the train from Durham Station to Portlandtrain train
    2. Fly from Portland (PWM) to Chicago Midway International Airport (MDW)plane plane PWM - MDW
    6h 37m
    $123–538

  7. Train to Portland, fly to Chicago O'Hare International Airport

    1. Take the train from Durham Station to Portlandtrain train
    2. Fly from Portland (PWM) to Chicago O'Hare International Airport (ORD)plane plane PWM - ORD
    7h 8m
    $108–468

  8. Train, bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the train from Durham Station to Bostontrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane plane MHT - MDW
    7h 50m
    $123–513

  9. Train, bus to Manchester Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Durham Station to Bostontrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Chicago O'Hare International Airport (ORD)plane plane MHT - ORD
    8h 24m
    $108–443

  10. Train to Boston Logan Airport, fly to General Mitchell International Airport, train

    1. Take the train from Durham Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)plane plane BOS - MKE
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 38m
    $704–3,415

Durham to Chicago by train and subway (Amtrak)

Calendar7Weekly Services
Duration24h 51mAverage Duration
Ticket$353Cheapest Price
See schedules

Questions & Answers

Map of how to get from Durham to Chicago.ExpandLaunch map view
  • Distance: 932.9 mi
  • Duration: 6h 11m

What companies run services between Durham, NH, USA and Chicago, IL, USA?

You can take a train from Durham Station to Chicago Union Station via Boston, North Station, Back Bay, and Boston in around 24h 51m. Alternatively, you can take a train from Durham Station to Chicago Bus Station via Dover, Dover Transportation Center, Hanover Station, Portsmouth Bus Stop, and New York Midtown in around 26h 48m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers