There are 9 ways to get from Durham (Station) to Tupelo by plane, car, bus (Flixbus, Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Golden Triangle Regional Airport, drive
best- Fly from Raleigh-Durham International Airport (RDU) to Golden Triangle Regional Airport (GTR)plane RDU - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
7h 10m$90–432Bus via Atlanta
- Take the bus from Durham to Atlanta Downtownbus FlixBus N2470
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
13h 38m$115–197Drive 655.4 mi
- Drive from Durham (Station) to Tupelocar 655.4 mi
11h 9m$120–173Fly Raleigh-Durham International Airport to Birmingham–Shuttlesworth International Airport, drive
- Fly from Raleigh-Durham International Airport (RDU) to Birmingham–Shuttlesworth International Airport (BHM)plane RDU - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
6h 18m$138–696Fly Raleigh-Durham International Airport to Tupelo Regional Airport
- Fly from Raleigh-Durham International Airport (RDU) to Tupelo Regional Airport (TUP)plane RDU - TUP
6h 10m$93–424Fly Raleigh-Durham International Airport to Memphis, bus
- Fly from Raleigh-Durham International Airport (RDU) to Memphis (MEM)plane RDU - MEM
- Take the bus from Memphis Bus Station to Tupelobus
8h 24m$161–800Train to Charlotte Douglas International Airport, fly to Northwest Alabama Regional Airport, drive
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Northwest Alabama Regional Airport (MSL)plane CLT - MSL
- Drive from Northwest Alabama Regional Airport (MSL) to Tupelocar
8h 27m$218–724Bus
- Take the bus from Durham to Atlanta Bus Stationbus FlixBus N2471 / ...
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
14h 34m$110–204Train, bus
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte Bus Station to Atlanta Downtownbus
- Take the bus from Atlanta Bus Station to Tupelobus
15h 28m$140–264
Raleigh-Durham International Airport (RDU) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Durham (Station) to Tupelo is to bus which costs $110 - $210 and takes 14h 34m.
The fastest way to get from Durham (Station) to Tupelo is to fly which takes 6h 10m and costs $90 - $430.
No, there is no direct bus from Durham (Station) to Tupelo. However, there are services departing from Durham and arriving at Tupelo via Atlanta Bus Station. The journey, including transfers, takes approximately 13h 38m.
The distance between Durham (Station) and Tupelo is 664 miles. The road distance is 659.2 miles.
The best way to get from Durham (Station) to Tupelo without a car is to bus via Atlanta which takes 13h 38m and costs $110 - $200.
It takes approximately 7h 10m to get from Durham (Station) to Tupelo, including transfers.
Durham (Station) to Tupelo bus services, operated by Flixbus USA, depart from Durham station.
The best way to get from Durham (Station) to Tupelo is to bus via Atlanta which takes 13h 38m and costs $110 - $200. Alternatively, you can fly, which costs $90 - $430 and takes 6h 10m.
Durham (Station) to Tupelo bus services, operated by Flixbus USA, arrive at Atlanta Downtown station.
Tupelo is 1h behind Durham (Station). It is currently 11:44 AM in Durham (Station) and 10:44 AM in Tupelo.
What companies run services between Durham (Station), NC, USA and Tupelo, MS, USA?
You can take a bus from Durham to Tupelo via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Tupelo in around 13h 38m. Alternatively, American Airlines, Corporate Flight Management Inc, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Tupelo Regional Airport (TUP) 3 times a day.
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $75–410
Flights from Raleigh-Durham International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Memphis via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $140–750
- Website
- contouraviation.com
Flights from Raleigh-Durham International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $75–400
Flights from Raleigh-Durham International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $140–600
Flights from Raleigh-Durham International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $80–430
Flights from Raleigh-Durham International Airport to Tupelo Regional Airport via Charlotte Douglas International Airport, Nashville
- Ave. Duration
- 7h 54m
- When
- Sunday and Thursday
- Estimated price
- $75–400
Flights from Charlotte Douglas International Airport to Northwest Alabama Regional Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $150–600
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Golden Triangle Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $140–650
Flights from Raleigh-Durham International Airport to Birmingham–Shuttlesworth International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $110–650
Flights from Raleigh-Durham International Airport to Memphis via Charlotte Douglas International Airport
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $130–750
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Birmingham–Shuttlesworth International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Tuesday and Wednesday
- Estimated price
- $170–850
Flights from Raleigh-Durham International Airport to Memphis via Nashville
- Ave. Duration
- 3h 35m
- When
- Sunday and Saturday
- Estimated price
- $130–750
Flights from Raleigh-Durham International Airport to Memphis via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–950
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h 40m
- When
- Monday and Friday
- Estimated price
- $250–1,700
Flights from Raleigh-Durham International Airport to Memphis
- Ave. Duration
- 2h
- When
- Monday and Friday
- Estimated price
- $280–1,800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Atlanta Downtown
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Every 4 hours
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Atlanta Downtown
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $35–65
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Durham to Atlanta Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- Every 4 hours
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Durham (Station) to Tupelo is 659 miles. It takes approximately 11h 9m to drive from Durham (Station) to Tupelo.
There are 31+ hotels available in Tupelo.








