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How to get fromDurham to Florenceby bus (Greyhound), train (Amtrak), car, plane, or train

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There are 5 ways to get from Durham to Florence by bus (Greyhound), train (Amtrak), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    4h 35m
    $28–46
  2. Train (Amtrak)

    1. Take the train from Durham Amtrak Station to Selma Stationtrain train Carolinian
    2. Take the train from Selma Station to Florence Stationtrain train Palmetto
    4h 59m
    $43–112
  3. Drive  150.4 mi

    1. Drive from Durham to Florencecar car 150.4 mi
    3h 24m
    $28–40
  4. Fly from Raleigh-Durham International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Florence Regional Airport (FLO)plane plane RDU - FLO
    5h 43m
    $59–348
  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Florence Regional Airport (FLO)plane plane CLT - FLO
    5h 51m
    $87–404

Durham to Florence by bus (Greyhound)

Calendar12Weekly Buses
Duration4h 35mAverage Duration
Ticket$28Cheapest Price
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Comparing Your Travel Options

What companies run services between Durham, NC, USA and Florence, SC, USA?

Greyhound USA operates a bus from Raleigh Bus Station to Florence Bus Station twice daily. Tickets cost $24–40 and the journey takes 3h. Alternatively, you can take a train from Durham Amtrak Station to Florence Station via Selma Station in around 4h 59m.

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