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How to get fromDurham to Greenvilleby train, bus, car, plane, bus (Greyhound, Flixbus), or taxi

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There are 7 ways to get from Durham to Greenville by train, bus, car, plane, bus (Greyhound, Flixbus), or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train Piedmont / ...
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    6h 42m
    $104–259

  2. Drive 238.5 mi

    cheapest
    1. Drive from Durham to Greenvillecar car 238.5 mi
    4h 9m
    $44–63

  3. Fly Raleigh-Durham International Airport to Greenville–Spartanburg International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP)plane plane RDU - GSP
    5h 46m
    $379–600

  4. Bus

    1. Take the bus from Durham to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    7h 4m
    $79–206

  5. Bus via Charlotte

    1. Take the bus from Durham, NC - 3446 Hillsborough Rd to Charlotte, NC - 3302 Queen City Drbus bus New York
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus Charlotte
    9h 29m
    $71–206

  6. Train to Charlotte Douglas International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Greenville–Spartanburg International Airport (GSP)plane plane CLT - GSP
    5h 58m
    $149–628

  7. Train to Charlotte Douglas International Airport, fly to Asheville Regional Airport, taxi

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane plane CLT - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 43m
    $234–603

Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) flights

Calendar109Weekly Planes
Duration3h 57mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

Map of how to get from Durham to Greenville.ExpandLaunch map view
  • Distance: 263.4 mi
  • Duration: 6h 42m

What companies run services between Durham, NC, USA and Greenville, SC, USA?

American Airlines, Delta, and three other airlines fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Durham to Greenville via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 7h 4m.

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