Rome2Rio

How to get fromDurham to Harrisburg, Paby bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

Find Transport to Harrisburg, Pa

See all options

There are 7 ways to get from Durham to Harrisburg, Pa by bus (Flixbus, Greyhound), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Durham to Washington Union Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    9h 5m
    $61–98

  2. Bus via Durham, NC - 3446 Hillsborough Rd

    cheapest
    1. Take the bus from Durham, NC - 3446 Hillsborough Rd to Washington, DC - 2305 Pennsylvania Avebus bus Charlotte
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    11h 19m
    $51–92

  3. Train, bus

    1. Take the train from Durham Amtrak Station to Washington Union Stationtrain train Carolinian
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    10h 59m
    $203–311

  4. Drive  365.4 mi

    1. Drive from Durham to Harrisburg, Pacar car 365.4 mi
    6h 37m
    $67–97

  5. Fly Raleigh-Durham International Airport to Harrisburg International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Harrisburg International Airport (MDT)plane plane RDU - MDT
    6h 28m
    $55–348

  6. Train to Charlotte Douglas International Airport, fly to Harrisburg International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Harrisburg International Airport (MDT)plane plane CLT - MDT
    7h 10m
    $148–503

  7. Fly Raleigh-Durham International Airport to Philadelphia International Airport, train

    1. Fly from Raleigh-Durham International Airport (RDU) to Philadelphia International Airport (PHL)plane plane RDU - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    7h 17m
    $136–270

Durham to Harrisburg, Pa by bus

Calendar4Weekly Buses
Duration9h 5mAverage Duration
Ticket$61Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Durham to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 374.2 mi
  • Duration: 9h 5m

What companies run services between Durham, NC, USA and Harrisburg, Pa, PA, USA?

You can take a bus from Durham to Harrisburg Bus Station via Washington Union Station in around 9h 5m. Alternatively, United Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Harrisburg International Airport (MDT) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There