There are 5 ways to get from Durham to Hartsville by bus (Flixbus), train (Amtrak), car, plane, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Raleigh Bus Station to Florencebus FlixBus N2472
4h 48m$86–117Drive 145.8 mi
cheapest- Drive from Durham to Hartsvillecar 145.8 mi
3h 8m$27–39Train (Amtrak)
- Take the train from Durham Amtrak Station to Selma Stationtrain Carolinian
- Take the train from Selma Station to Florence Stationtrain Palmetto
5h 34m$125–202Fly, taxi
- Fly from Raleigh-Durham International Airport (RDU) to Florence Regional Airport (FLO)plane RDU - FLO
- Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi
6h 18m$129–426Bus via Regional Transit Center (Greyhound)
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus Greyhound US0642S / ...
6h 26m$105–148
Raleigh-Durham International Airport (RDU) to Florence Regional Airport (FLO) flights
Questions & Answers
The cheapest way to get from Durham to Hartsville is to drive which costs $26 - $40 and takes 3h 8m.
The fastest way to get from Durham to Hartsville is to drive which takes 3h 8m and costs $26 - $40.
No, there is no direct bus from Durham to Hartsville. However, there are services departing from Durham and arriving at Florence via Raleigh Bus Station. The journey, including transfers, takes approximately 4h 48m.
No, there is no direct train from Durham station to Hartsville station. However, there are services departing from Durham Amtrak Station and arriving at Florence Station via Selma Station. The journey, including transfers, takes approximately 5h 34m.
The distance between Durham and Hartsville is 194 miles. The road distance is 146.6 miles.
The best way to get from Durham to Hartsville without a car is to bus which takes 4h 48m and costs $85 - $120.
It takes approximately 4h 48m to get from Durham to Hartsville, including transfers.
Durham to Hartsville bus services, operated by Flixbus USA, depart from Raleigh Bus Station.
Durham to Hartsville train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Hartsville is to bus which takes 4h 48m and costs $85 - $120. Alternatively, you can train, which costs $120 - $210 and takes 5h 34m.
What companies run services between Durham, NC, USA and Hartsville, SC, USA?
Flixbus USA operates a bus from Raleigh Bus Station to Florence 5 times a week. Tickets cost $22–35 and the journey takes 2h 45m. Alternatively, you can take a train from Durham Amtrak Station to Hartsville via Selma Station and Florence Station in around 5h 34m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $45–320
Flights from Raleigh-Durham International Airport to Florence Regional Airport via Reagan Washington, Charlotte
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $75–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Selma Station
- Ave. Duration
- 1h 19m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Amtrak
Train from Selma Station to Florence Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Raleigh Bus Station to Florence
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a week
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
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More Questions & Answers
Durham to Hartsville bus services, operated by Flixbus USA, arrive at Florence station.
Durham to Hartsville train services, operated by Amtrak, arrive at Selma Station.
Yes, the driving distance between Durham to Hartsville is 147 miles. It takes approximately 3h 8m to drive from Durham to Hartsville.
There are seven+ hotels available in Hartsville.