There are 8 ways to get from Durham to Lowell by bus, plane, train, bus (Flixbus, Greyhound), train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly to Boston Logan Airport, train
best- Take the bus from Durham Station to Regional Transit Centerbus
- Fly from Raleigh-Durham International Airport (RDU) to Boston Logan Airport (BOS)plane RDU - BOS
- Take the train from Anderson/Woburn to Lowelltrain
6h 7m$155–972Bus via Boston
cheapest- Take the bus from Durham to New York, NYbus
- Take the bus from NYC Downtown to Bostonbus
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus
15h 7m$110–166Train via New York
- Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from North Station to Lowelltrain
17h 1m$245–517Drive 690.1 mi
- Drive from Durham to Lowellcar 690.1 mi
12h 33m$126–182Fly to Theodore Francis Green State Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Theodore Francis Green State Airport (PVD)plane RDU - PVD
- Take the train from TF Green Airport to Rugglestrain
- Take the train from North Station to Lowelltrain
8h 13m$140–476Fly to Manchester Airport, bus, train
- Fly from Raleigh-Durham International Airport (RDU) to Manchester Airport (MHT)plane RDU - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the train from North Station to Lowelltrain
8h 23m$148–634Train
- Take the train from Durham Amtrak Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Bostontrain
- Take the train from North Station to Lowelltrain
17h 58m$246–517Bus (Greyhound)
- Take the bus from Durham to Port Authority Bus Terminalbus Greyhound US0670
- Take the bus from Port Authority Bus Terminal to Robert B Kennedy Bus Transfer Centerbus Greyhound US0256S
22h 10m$118–231
Durham to Lowell by train and subway
Questions & Answers
The cheapest way to get from Durham to Lowell is to bus via Boston which costs $110 - $170 and takes 15h 7m.
The fastest way to get from Durham to Lowell is to bus and fly and train which takes 6h 7m and costs $150 - $1,000.
No, there is no direct bus from Durham to Lowell. However, there are services departing from Durham and arriving at Robert B Kennedy Bus Transfer Center via NYC Downtown and Boston. The journey, including transfers, takes approximately 15h 7m.
No, there is no direct train from Durham station to Lowell. However, there are services departing from Durham Amtrak Station and arriving at Lowell via Ny Moynihan Train Hall At Penn Station, Back Bay and North Station. The journey, including transfers, takes approximately 17h 1m.
The distance between Durham and Lowell is 660 miles. The road distance is 694.2 miles.
The best way to get from Durham to Lowell without a car is to bus via Boston which takes 15h 7m and costs $110 - $170.
It takes approximately 6h 7m to get from Durham to Lowell, including transfers.
Durham to Lowell bus services, operated by Wanda Coach, depart from Durham station.
Durham to Lowell train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Lowell is to bus via Boston which takes 15h 7m and costs $110 - $170. Alternatively, you can train via New York, which costs $240 - $550 and takes 17h 1m.
What companies run services between Durham, NC, USA and Lowell, MA, USA?
You can take a bus from Durham to Robert B Kennedy Bus Transfer Center via New York, NY, NYC Downtown, and Boston in around 15h 7m. Alternatively, you can take a train from Durham Amtrak Station to Lowell via Ny Moynihan Train Hall At Penn Station, Boston, Back Bay, North Station, and North Station in around 17h 1m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Boston Logan Airport via Reagan Washington
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $70–400
Flights from Raleigh-Durham International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 4h
- When
- Tuesday and Wednesday
- Estimated price
- $70–400
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $50–290
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $50–290
Flights from Raleigh-Durham International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $80–440
Flights from Raleigh-Durham International Airport to Manchester Airport via Charlotte
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $95–500
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 41m
- When
- Tuesday to Friday
- Estimated price
- $70–400
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $50–290
Flights from Raleigh-Durham International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $80–440
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Boston Logan Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $70–400
- Website
- united.com
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $50–300
Flights from Raleigh-Durham International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $80–440
- Website
- jetblue.com
Flights from Raleigh-Durham International Airport to Boston Logan Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $70–400
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Theodore Francis Green State Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $120–440
Flights from Raleigh-Durham International Airport to Manchester Airport
- Ave. Duration
- 1h 55m
- When
- Thursday and Sunday
- Estimated price
- $130–600
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to Boston Logan Airport
- Ave. Duration
- 2h 6m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $140–450
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from TF Green Airport to Ruggles
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 11h 8m
- Frequency
- Once daily
- Estimated price
- $160–360
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $70–150
- Website
- Amtrak
Train from Durham Amtrak Station to Petersburg Amtrak Station
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- Amtrak
Train from Petersburg Amtrak Station to Boston
- Ave. Duration
- 11h 40m
- Frequency
- 5 times a week
- Estimated price
- $180–380
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 919-485-7433
- Website
- godurhamtransit.org
Bus from Durham Station to Regional Transit Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Schedules at
- godurhamtransit.org
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Durham to New York, NY
- Ave. Duration
- 7h 22m
- Frequency
- Every 4 hours
- Estimated price
- $75–110
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $75–110
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from NYC Downtown to Boston
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Durham to Port Authority Bus Terminal
- Ave. Duration
- 12h 55m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 8h 15m
- Frequency
- 5 times a week
- Estimated price
- $35–75
- Website
- Greyhound
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More Questions & Answers
Durham to Lowell bus services, operated by Wanda Coach, arrive at New York, NY station.
Durham to Lowell train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Durham to Lowell is 694 miles. It takes approximately 12h 33m to drive from Durham to Lowell.
Book your Durham to Lowell bus tickets online with Omio.
There are 105+ hotels available in Lowell.














