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How to get fromDurham to Mississaugaby bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound)

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There are 9 ways to get from Durham to Mississauga by bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Raleigh-Durham International Airport, fly to Toronto Pearson International Airport

    best
    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Toronto Pearson International Airport (YYZ)plane plane RDU - YYZ
    5h 45m
    $760–2,215

  2. Fly Raleigh-Durham International Airport to Toronto Island Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Toronto Island Airport (YTZ)plane plane RDU - YTZ
    8h 46m
    $103–569

  3. Bus

    1. Take the bus from Durham to New York Midtownbus bus FlixBus N2471 / ...
    2. Take the bus from New York to Mississaugabus bus Adt N816-D / ...
    22h 19m
    $221–645

  4. Train

    1. Take the train from Durham Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Carolinian
    2. Take the train from New York Penn Station to Oakvilletrain train VIA Rail
    24h 55m
    $394–920

  5. Drive  1,064.6 km

    1. Drive from Durham to Mississaugacar car 1,064.6 km
    14h 5m
    $216–312

  6. Fly Raleigh-Durham International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    2. Take the bus from Buffalo to Mississaugabus bus
    8h 19m
    $209–694

  7. Train to Piedmont Triad International Airport, fly to Toronto Pearson International Airport

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Toronto Pearson International Airport (YYZ)plane plane GSO - YYZ
    7h 53m
    $169–707

  8. Train to Charlotte Douglas International Airport, fly to Toronto Pearson International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Toronto Pearson International Airport (YYZ)plane plane CLT - YYZ
    8h 9m
    $149–686

  9. Bus via Union Station Bus Terminal (Greyhound)

    1. Take the bus from Durham to Port Authority Bus Terminalbus bus Greyhound US0670
    2. Take the bus from Port Authority Bus Terminal to Torontobus bus Greyhound US0215
    27h 33m
    $242–394

Durham to Mississauga by bus

Calendar11Weekly Buses
Duration22h 19mAverage Duration
Ticket$221Cheapest Price
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Comparing Your Travel Options

Map of how to get from Durham to Mississauga.ExpandLaunch map view
  • Distance: 912.3 km
  • Duration: 5h 45m

What companies run services between Durham, NC, USA and Mississauga, ON, Canada?

You can take a bus from Durham to City Centre Transit Terminal Platform A via New York Midtown, 8 Av/W 31 St, 8 Av/W 41 St, New York, and Winston Churchill Station East Platform 6 in around 22h 19m. Alternatively, you can take a train from Durham Amtrak Station to University Of Toronto At Mississauga Campus via Ny Moynihan Train Hall At Penn Station, New York Penn Station, Oakville, Oakville GO, Clarkson GO, and Clarkson Go Station Platform 9 in around 24h 55m.

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