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How to get fromDurham to Mount Pleasantby train (Amtrak), car, bus, plane, or train

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There are 6 ways to get from Durham to Mount Pleasant by train (Amtrak), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Durham Amtrak Station to Selma Stationtrain train Carolinian
    2. Take the train from Selma Station to Charleston Amtrak Stationtrain train Palmetto
    6h 54m
    $128–236

  2. Drive 253.3 mi

    cheapest
    1. Drive from Durham to Mount Pleasantcar car 253.3 mi
    5h 32m
    $47–67

  3. Bus to Raleigh-Durham International Airport, fly to Charleston International Airport, line 41 bus

    1. Take the bus from Durham Station to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS)plane plane RDU - CHS
    3. Take the bus from Mary St / Meeting St to Coleman Blvd / Chuck Dawley Blvdbus bus
    8h 26m
    $258–610

  4. Bus to Piedmont Triad International Airport, fly to Charleston International Airport

    1. Take the bus from Durham to Greensboro Bus Stopbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)plane plane GSO - CHS
    8h 21m
    $352–1,360

  5. Train to Charlotte Douglas International Airport, fly to Charleston International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane plane CLT - CHS
    8h 52m
    $108–476

  6. Train to Charlotte Douglas International Airport, fly to Hilton Head Airport, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Hilton Head Airport (HHH)plane plane CLT - HHH
    3. Drive from Hilton Head Airport (HHH) to Mount Pleasantcar car
    8h 25m
    $123–481

Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS) flights

Calendar125Weekly Planes
Duration3h 57mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

Map of how to get from Durham to Mount Pleasant.ExpandLaunch map view
  • Distance: 292 mi
  • Duration: 6h 54m

What companies run services between Durham, NC, USA and Mount Pleasant, SC, USA?

You can take a train from Durham Amtrak Station to Mount Pleasant via Selma Station and Charleston Amtrak Station in around 6h 54m.

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Train operators
Bus operators

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