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How to get fromDurham to Mount Pleasantby train (Amtrak), car, plane, or train

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There are 8 ways to get from Durham to Mount Pleasant by train (Amtrak), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Durham Amtrak Station to Selma Stationtrain train Carolinian
    2. Take the train from Selma Station to Charleston Amtrak Stationtrain train Palmetto
    6h 54m
    $190–296

  2. Drive  253.3 mi

    cheapest
    1. Drive from Durham to Mount Pleasantcar car 253.3 mi
    5h 32m
    $44–63

  3. Fly Raleigh-Durham International Airport to Charleston International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS)plane plane RDU - CHS
    8h 30m
    $68–420

  4. Train to Piedmont Triad International Airport, fly to Charleston International Airport

    1. Take the train from Durham Amtrak Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Charleston International Airport (CHS)plane plane GSO - CHS
    8h 25m
    $119–480

  5. Fly Raleigh-Durham International Airport to Charlotte Douglas International Airport, drive

    1. Fly from Raleigh-Durham International Airport (RDU) to Charlotte Douglas International Airport (CLT)plane plane RDU - CLT
    2. Drive from Charlotte-Airport-CLT to Mount Pleasantcar car
    7h 5m
    $99–520

  6. Train to Charlotte Douglas International Airport, fly to Columbia, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane plane CLT - CAE
    3. Drive from Columbia-Airport-CAE to Mount Pleasantcar car
    7h 38m
    $146–479

  7. Train to Charlotte Douglas International Airport, fly to Charleston International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane plane CLT - CHS
    8h 44m
    $146–544

  8. Train to Charlotte Douglas International Airport, fly to Hilton Head Airport, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Hilton Head Airport (HHH)plane plane CLT - HHH
    3. Drive from Hilton Head Airport (HHH) to Mount Pleasantcar car
    8h 20m
    $150–497

Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS) flights

Calendar100Weekly Planes
Duration3h 51mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Durham to Mount Pleasant.ExpandLaunch map view
  • Distance: 292 mi
  • Duration: 6h 54m

What companies run services between Durham, NC, USA and Mount Pleasant, SC, USA?

You can take a train from Durham Amtrak Station to Mount Pleasant via Selma Station and Charleston Amtrak Station in around 6h 54m. Alternatively, American Airlines, United Airlines, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS) hourly.

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Train operators

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