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How to get fromDurham to Orangeburgby train (Amtrak), bus (Greyhound, Flixbus), car, plane, taxi, train, bus, or bus (Greyhound)

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There are 8 ways to get from Durham to Orangeburg by train (Amtrak), bus (Greyhound, Flixbus), car, plane, taxi, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Cary to Denmark Amtrak Stationtrain train Floridian
    7h 10m
    $129–230

  2. Drive  239.4 mi

    cheapest
    1. Drive from Durham to Orangeburgcar car 239.4 mi
    4h 47m
    $44–64

  3. Bus via Charlotte

    1. Take the bus from Durham to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus Greyhound US0644S / ...
    7h 38m
    $55–90

  4. Fly from Raleigh-Durham International Airport, taxi

    1. Fly from Raleigh-Durham International Airport (RDU) to Columbia (CAE)plane plane RDU - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 24m
    $169–486

  5. Train, bus

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train Piedmont / ...
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus Greyhound US0644S / ...
    8h 12m
    $74–145

  6. Bus

    1. Take the bus from Durham to Camdenbus bus Nyc
    2. Take the bus from Camden to Orangeburgbus bus Greyhound US0644S
    8h 47m
    $62–93

  7. Bus #2 (Greyhound)

    1. Take the bus from Raleigh Bus Station to Orangeburgbus bus Greyhound US0645S
    9h 5m
    $54–88

  8. Train to Charlotte Douglas International Airport, fly, taxi

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane plane CLT - CAE
    3. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 25m
    $198–540

Raleigh-Durham International Airport (RDU) to Columbia (CAE) flights

Calendar172Weekly Planes
Duration4h 26mAverage Duration
Ticket$47Cheapest Price
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Comparing Your Travel Options

Map of how to get from Durham to Orangeburg.ExpandLaunch map view
  • Distance: 283.7 mi
  • Duration: 7h 10m

What companies run services between Durham, NC, USA and Orangeburg, SC, USA?

Amtrak operates a train from Cary to Denmark Amtrak Station once daily. Tickets cost $60–140 and the journey takes 5h 14m. Alternatively, you can take a bus from Durham to Orangeburg via Charlotte Bus Station and Orangeburg in around 7h 38m.

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