There are 7 ways to get from Durham to Orangeburg by train (Amtrak), bus (Greyhound, Flixbus), car, plane, taxi, bus (Greyhound), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Cary to Denmark Amtrak Stationtrain Floridian
7h 10m$135–241Drive 239.4 mi
cheapest- Drive from Durham to Orangeburgcar 239.4 mi
4h 46m$44–64Bus via Charlotte
- Take the bus from Durham to Charlotte Bus Stationbus Greyhound US0670
- Take the bus from Charlotte Bus Station to Orangeburgbus Greyhound US0644S / ...
7h 48m$51–93Fly from Raleigh-Durham International Airport, taxi
- Fly from Raleigh-Durham International Airport (RDU) to Columbia (CAE)plane RDU - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
6h 14m$169–476Bus
- Take the bus from Durham to Camdenbus Nyc
- Take the bus from Camden to Orangeburgbus Greyhound US0644S
8h 47m$61–95Bus #2 (Greyhound)
- Take the bus from Raleigh Bus Station to Orangeburgbus Greyhound US0645S
9h 5m$54–92Train to Charlotte Douglas International Airport, fly, taxi
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane CLT - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
6h 27m$202–565
Raleigh-Durham International Airport (RDU) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Durham to Orangeburg is to drive which costs $40 - $65 and takes 4h 46m.
The fastest way to get from Durham to Orangeburg is to drive which takes 4h 46m and costs $40 - $65.
No, there is no direct bus from Durham to Orangeburg. However, there are services departing from Durham and arriving at Orangeburg via Charlotte Bus Station. The journey, including transfers, takes approximately 7h 48m.
No, there is no direct train from Durham station to Orangeburg station. However, there are services departing from Durham Amtrak Station and arriving at Denmark Amtrak Station via Cary. The journey, including transfers, takes approximately 7h 10m.
The distance between Durham and Orangeburg is 285 miles. The road distance is 240.8 miles.
The best way to get from Durham to Orangeburg without a car is to train which takes 7h 10m and costs $130 - $250.
It takes approximately 7h 10m to get from Durham to Orangeburg, including transfers.
Durham to Orangeburg bus services, operated by Greyhound USA, depart from Durham station.
Durham to Orangeburg train services, operated by Amtrak, depart from Cary station.
The best way to get from Durham to Orangeburg is to train which takes 7h 10m and costs $130 - $250. Alternatively, you can bus via Charlotte, which costs $50 - $95 and takes 7h 48m.
What companies run services between Durham, NC, USA and Orangeburg, SC, USA?
Amtrak operates a train from Cary to Denmark Amtrak Station once daily. Tickets cost $65–150 and the journey takes 5h 14m. Alternatively, you can take a bus from Durham to Orangeburg via Charlotte Bus Station and Orangeburg in around 7h 48m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Columbia via Charlotte Douglas International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $45–320
Flights from Raleigh-Durham International Airport to Columbia via Reagan Washington
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–410
Flights from Raleigh-Durham International Airport to Columbia via Philadelphia
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–460
Flights from Raleigh-Durham International Airport to Columbia via New York La Guardia
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Charlotte Douglas International Airport to Columbia
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $35–320
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Columbia via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $70–390
- Website
- united.com
Flights from Raleigh-Durham International Airport to Columbia via Washington Dulles
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $75–410
Flights from Raleigh-Durham International Airport to Columbia via Newark
- Ave. Duration
- 4h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cary to Denmark Amtrak Station
- Ave. Duration
- 5h 14m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $40–90
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Durham to Charlotte Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $20–40
- Website
- Greyhound
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $23–45
- Website
- Greyhound
Bus from Camden to Orangeburg
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- Greyhound
Bus from Raleigh Bus Station to Orangeburg
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Charlotte Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- 4 times a day
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Durham to Camden
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
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More Questions & Answers
Durham to Orangeburg bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Durham to Orangeburg train services, operated by Amtrak, arrive at Denmark Amtrak Station.
Yes, the driving distance between Durham to Orangeburg is 241 miles. It takes approximately 4h 46m to drive from Durham to Orangeburg.
Book your Durham to Orangeburg bus tickets online with Omio.
There are 21+ hotels available in Orangeburg.








