There are 8 ways to get from Durham to Palo Alto by plane, bus (Flixbus, Greyhound), train, subway, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to San Francisco International Airport
best- Fly from Raleigh-Durham International Airport (RDU) to San Francisco International Airport (SFO)plane RDU - SFO
8h 59m$197–424Bus
- Take the bus from Durham to Washington Union Stationbus
- Take the bus from Washington Union Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Denver Union Stationbus
- Take the bus from Denver Union Station to Sparks Transit Centerbus
- Take the bus from Sparks Transit Center to San Francisco Bus Stationbus
- Take the bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctrbus
3d 5h$517–839Train, BART
- Take the train from Durham Amtrak Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Richmondtrain
- Take the subway from Richmond to Millbraesubway
3d 10h$1,881–3,045Drive 2,760.9 mi
- Drive from Durham to Palo Altocar 2,760.9 mi
45h$504–728Fly Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport
- Fly from Raleigh-Durham International Airport (RDU) to Norman Y. Mineta San José International Airport (SJC)plane RDU - SJC
10h 37m$201–864Train to Piedmont Triad International Airport, fly to San Francisco International Airport
- Take the train from Durham Amtrak Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to San Francisco International Airport (SFO)plane GSO - SFO
10h 36m$223–754Train to Charlotte Douglas International Airport, fly to San Francisco International Airport
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to San Francisco International Airport (SFO)plane CLT - SFO
11h 21m$220–518Fly Raleigh-Durham International Airport to Oakland International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Oakland International Airport (OAK)plane RDU - OAK
- Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain
12h 16m$220–850
Durham to Palo Alto by bus
Comparing Your Travel Options
The cheapest way to get from Durham to Palo Alto is to fly which costs $190 - $430 and takes 8h 59m.
The fastest way to get from Durham to Palo Alto is to fly which takes 8h 59m and costs $190 - $430.
No, there is no direct bus from Durham to Palo Alto. However, there are services departing from Durham and arriving at Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Washington Union Station, Chicago Bus Station, Denver Union Station, Sparks Transit Center and Salesforce Transit Center- Bay 37. The journey, including transfers, takes approximately 3 days 5h.
No, there is no direct train from Durham station to Palo Alto. However, there are services departing from Durham Amtrak Station and arriving at California Avenue Caltrain Southbound via Raleigh Union Station, Chicago Union Station, Richmond and Millbrae Caltrain Southbound. The journey, including transfers, takes approximately 3 days 10h.
The distance between Durham and Palo Alto is 2446 miles. The road distance is 2777 miles.
The best way to get from Durham to Palo Alto without a car is to bus which takes 3 days 5h and costs $500 - $850.
It takes approximately 8h 59m to get from Durham to Palo Alto, including transfers.
Durham to Palo Alto bus services, operated by Flixbus USA, depart from Durham station.
Durham to Palo Alto train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to Palo Alto is to fly which takes 8h 59m and costs $190 - $430. Alternatively, you can bus, which costs $500 - $850 and takes 3 days 5h.
What companies run services between Durham, NC, USA and Palo Alto, CA, USA?
United Airlines, Southwest Airlines, and Frontier Airlines fly from Raleigh-Durham International Airport (RDU) to San Francisco International Airport (SFO) every 4 hours. Alternatively, you can take a bus from Durham to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Washington Union Station, Chicago Bus Station, Denver Union Station, Sparks Transit Center, San Francisco Bus Station, and Salesforce Transit Center- Bay 37 in around 3d 5h.
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to San Francisco International Airport via St. Louis
- Ave. Duration
- 7h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $130–600
Flights from Raleigh-Durham International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 46m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–600
Flights from Raleigh-Durham International Airport to San Francisco International Airport via Las Vegas
- Ave. Duration
- 8h 50m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $140–600
Flights from Raleigh-Durham International Airport to San Francisco International Airport via Nashville
- Ave. Duration
- 8h 25m
- When
- Tuesday to Friday
- Estimated price
- $130–600
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Nashville
- Ave. Duration
- 7h 20m
- When
- Saturday
- Estimated price
- $190–850
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 8h 38m
- When
- Every day
- Estimated price
- $190–850
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Chicago Midway
- Ave. Duration
- 7h 47m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- $200–850
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 8h 5m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $190–850
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 9h 6m
- When
- Every day
- Estimated price
- $200–850
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Dallas
- Ave. Duration
- 9h 55m
- When
- Tuesday and Wednesday
- Estimated price
- $200–850
Flights from Raleigh-Durham International Airport to Oakland International Airport via Denver
- Ave. Duration
- 8h 36m
- When
- Sunday and Saturday
- Estimated price
- $190–800
Flights from Raleigh-Durham International Airport to Oakland International Airport via Chicago Midway
- Ave. Duration
- 7h 48m
- When
- Sunday and Saturday
- Estimated price
- $200–850
Flights from Raleigh-Durham International Airport to Oakland International Airport via Dallas
- Ave. Duration
- 7h 40m
- When
- Saturday
- Estimated price
- $200–850
Flights from Raleigh-Durham International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 8h 41m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $190–850
Flights from Raleigh-Durham International Airport to Oakland International Airport via Phoenix
- Ave. Duration
- 10h 38m
- When
- Every day
- Estimated price
- $200–850
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 11h 5m
- When
- Monday and Friday
- Estimated price
- $200–850
Flights from Piedmont Triad International Airport to San Francisco International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 8h 5m
- When
- Every day
- Estimated price
- $150–650
Flights from Piedmont Triad International Airport to San Francisco International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 48m
- When
- Every day
- Estimated price
- $160–700
Flights from Piedmont Triad International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 9h 19m
- When
- Every day
- Estimated price
- $160–700
Flights from Piedmont Triad International Airport to San Francisco International Airport via Philadelphia
- Ave. Duration
- 9h 4m
- When
- Every day
- Estimated price
- $180–750
Flights from Charlotte Douglas International Airport to San Francisco International Airport
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $120–550
- Website
- united.com
Flights from Raleigh-Durham International Airport to San Francisco International Airport
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $130–600
Flights from Raleigh-Durham International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 48m
- When
- Every day
- Estimated price
- $130–600
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 56m
- When
- Every day
- Estimated price
- $190–850
Flights from Piedmont Triad International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $160–700
Flights from Piedmont Triad International Airport to San Francisco International Airport via Washington Dulles
- Ave. Duration
- 8h 28m
- When
- Every day
- Estimated price
- $170–700
Flights from Charlotte Douglas International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 8h 41m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Norman Y. Mineta San José International Airport via Salt Lake City
- Ave. Duration
- 8h 43m
- When
- Every day
- Estimated price
- $190–850
Flights from Piedmont Triad International Airport to San Francisco International Airport via Atlanta
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $160–700
Flights from Piedmont Triad International Airport to San Francisco International Airport via Detroit
- Ave. Duration
- 11h 20m
- When
- Every day
- Estimated price
- $160–700
Flights from Raleigh-Durham International Airport to Oakland International Airport via Salt Lake City
- Ave. Duration
- 7h 57m
- When
- Every day
- Estimated price
- $190–850
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 9h 56m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $130–390
Flights from Charlotte Douglas International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 10h 28m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $120–370
- Website
- alaskaair.com
Flights from Raleigh-Durham International Airport to Oakland International Airport via San Diego
- Ave. Duration
- 9h 20m
- When
- Every day
- Estimated price
- $280–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Durham Amtrak Station to Raleigh Union Station
- Ave. Duration
- 39 min
- Frequency
- 5 times a day
- Estimated price
- $14–22
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Richmond
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $1,300–2,100
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $29–50
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $80–130
- Website
- Amtrak
Train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtrak
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Website
- Amtrak
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Richmond to Millbrae
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- $12–16
- Website
- BART
- Adult Single Ride
- $12–16
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Durham to Washington Union Station
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Durham to Washington Union Station
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Washington Union Station to Chicago Bus Station
- Ave. Duration
- 17h 10m
- Frequency
- Twice daily
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Chicago Bus Station to Denver Union Station
- Ave. Duration
- 21h 35m
- Frequency
- Once daily
- Estimated price
- $160–260
- Website
- Greyhound
Bus from Denver Union Station to Sparks Transit Center
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- $170–270
- Website
- Greyhound
Bus from Sparks Transit Center to San Francisco Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- 1-800-660-4287
- [email protected]
- Website
- SamTrans Homepage
Bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr
- Ave. Duration
- 1h 36m
- Frequency
- 4 times a day
- Estimated price
- $3
- Website
- SamTrans Homepage
- Schedules at
- SamTrans Schedules
- Single Fare
- $3
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Booking & Getting There
Durham to Palo Alto bus services, operated by Flixbus USA, arrive at Washington Union Station.
Palo Alto is 3h behind Durham. It is currently 4:57 PM in Durham and 1:57 PM in Palo Alto.
Durham to Palo Alto train services, operated by Amtrak, arrive at Raleigh Union Station.
Yes, the driving distance between Durham to Palo Alto is 2777 miles. It takes approximately 45h to drive from Durham to Palo Alto.
There are 486+ hotels available in Palo Alto.











