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How to get fromDurham to Panama Cityby plane, car, bus, or train

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There are 6 ways to get from Durham to Panama City by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Northwest Florida Beaches International Airport (ECP)plane plane RDU - ECP
    6h 29m
    $139–486

  2. Fly Raleigh-Durham International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Destin–Fort Walton Beach Airport (VPS)plane plane RDU - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    7h 19m
    $91–434

  3. Drive 625 mi

    1. Drive from Durham to Panama Citycar car 625 mi
    13h 12m
    $115–165

  4. Bus to Piedmont Triad International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Durham to Greensboro Bus Stopbus bus
    2. Fly from Piedmont Triad International Airport (GSO) to Northwest Florida Beaches International Airport (ECP)plane plane GSO - ECP
    6h 16m
    $188–605

  5. Fly Raleigh-Durham International Airport to Tallahassee, drive

    1. Fly from Raleigh-Durham International Airport (RDU) to Tallahassee (TLH)plane plane RDU - TLH
    2. Drive from Tallahassee (TLH) to Panama Citycar car
    6h
    $106–522

  6. Train to Charlotte Douglas International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Northwest Florida Beaches International Airport (ECP)plane plane CLT - ECP
    7h 4m
    $188–602

Raleigh-Durham International Airport (RDU) to Northwest Florida Beaches International Airport (ECP) flights

Calendar75Weekly Planes
Duration4h 52mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Durham to Panama City.ExpandLaunch map view
  • Distance: 596.4 mi
  • Duration: 6h 29m

What companies run services between Durham, NC, USA and Panama City, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

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