Rome2Rio

How to get fromDurham to Port Saint Lucieby plane, taxi, bus (Flixbus), train, bus, or car

Find Transport to Port Saint Lucie

See all options

There are 6 ways to get from Durham to Port Saint Lucie by plane, taxi, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Vero Beach Municipal Airport, taxi

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Vero Beach Municipal Airport (VRB)plane plane RDU - VRB
    2. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    5h 1m
    $234–916
  2. Fly to Orlando, bus

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to Orlando (MCO)plane plane RDU - MCO
    2. Take the bus from Orlando RedCoach Station to Fort Piercebus bus
    7h 17m
    $99–352
  3. Bus

    1. Take the bus from Raleigh Bus Station to Orlando Bus Stationbus bus FlixBus N2472
    2. Take the bus from Orlando RedCoach Station to Fort Piercebus bus Orlando–Miami / ...
    17h 12m
    $129–224
  4. Train, bus

    1. Take the train from Cary to Kissimmee Amtrak Stationtrain train Floridian
    2. Take the bus from Kissimmee to Fort Piercebus bus Tallahassee–Miami via Orlando
    19h 31m
    $248–474
  5. Drive 689.8 mi

    1. Drive from Durham to Port Saint Luciecar car 689.8 mi
    12h 3m
    $126–182
  6. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane RDU - FLL
    2. Take the bus from Fort Lauderdale Airport to Fort Piercebus bus
    7h 3m
    $198–900

Durham to Port Saint Lucie by bus

Calendar12Weekly Buses
Duration17h 12mAverage Duration
Ticket$129Cheapest Price
See schedules

Questions & Answers

What companies run services between Durham, NC, USA and Port Saint Lucie, FL, USA?

You can take a bus from Durham to Fort Pierce via Raleigh Bus Station, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, Mccoy Rd & Central Ave, and Orlando RedCoach Station in around 17h 12m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound