There are 6 ways to get from Durham to Port Saint Lucie by plane, taxi, bus (Flixbus), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Vero Beach Municipal Airport, taxi
best- Fly from Raleigh-Durham International Airport (RDU) to Vero Beach Municipal Airport (VRB)plane RDU - VRB
- Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi
5h 1m$234–916Fly to Orlando, bus
cheapest- Fly from Raleigh-Durham International Airport (RDU) to Orlando (MCO)plane RDU - MCO
- Take the bus from Orlando RedCoach Station to Fort Piercebus
7h 17m$99–352Bus
- Take the bus from Raleigh Bus Station to Orlando Bus Stationbus FlixBus N2472
- Take the bus from Orlando RedCoach Station to Fort Piercebus Orlando–Miami / ...
17h 12m$129–224Train, bus
- Take the train from Cary to Kissimmee Amtrak Stationtrain Floridian
- Take the bus from Kissimmee to Fort Piercebus Tallahassee–Miami via Orlando
19h 31m$248–474Drive 689.8 mi
- Drive from Durham to Port Saint Luciecar 689.8 mi
12h 3m$126–182Fly to Fort Lauderdale–Hollywood International Airport, bus
- Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)plane RDU - FLL
- Take the bus from Fort Lauderdale Airport to Fort Piercebus
7h 3m$198–900
Durham to Port Saint Lucie by bus
Questions & Answers
The cheapest way to get from Durham to Port Saint Lucie is to drive which costs $120 - $190 and takes 12h 3m.
The fastest way to get from Durham to Port Saint Lucie is to fly and taxi which takes 5h 1m and costs $230 - $950.
No, there is no direct bus from Durham to Port Saint Lucie. However, there are services departing from Durham and arriving at Fort Pierce via Raleigh Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St and Orlando RedCoach Station. The journey, including transfers, takes approximately 17h 12m.
The distance between Durham and Port Saint Lucie is 624 miles. The road distance is 693.8 miles.
The best way to get from Durham to Port Saint Lucie without a car is to bus which takes 17h 12m and costs $120 - $230.
It takes approximately 5h 1m to get from Durham to Port Saint Lucie, including transfers.
Durham to Port Saint Lucie bus services, operated by FlixBus-us, depart from Raleigh Bus Station.
Durham to Port Saint Lucie bus services, operated by FlixBus-us, arrive at Orlando Bus Station.
Yes, the driving distance between Durham to Port Saint Lucie is 694 miles. It takes approximately 12h 3m to drive from Durham to Port Saint Lucie.
There are 412+ hotels available in Port Saint Lucie.
What companies run services between Durham, NC, USA and Port Saint Lucie, FL, USA?
You can take a bus from Durham to Fort Pierce via Raleigh Bus Station, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, Mccoy Rd & Central Ave, and Orlando RedCoach Station in around 17h 12m.
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Orlando
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $70–380
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h
- When
- Sunday
- Estimated price
- $85–440
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $85–440
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $90–460
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Orlando
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $70–380
Flights from Raleigh-Durham International Airport to Orlando via Atlanta
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $85–430
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $85–440
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–500
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Vero Beach Municipal Airport
- Ave. Duration
- 2h
- When
- Wednesday and Saturday
- Estimated price
- $140–800
Flights from Raleigh-Durham International Airport to Orlando
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $60–290
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Vero Beach Municipal Airport via Charlotte
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $100–550
Flights from Raleigh-Durham International Airport to Orlando via Charlotte
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $75–400
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $90–460
- Website
- flyfrontier.com
Flights from Raleigh-Durham International Airport to Orlando
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $70–220
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 8m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–460
- Website
- jetblue.com
Flights from Raleigh-Durham International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $85–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cary to Kissimmee Amtrak Station
- Ave. Duration
- 14h 22m
- Frequency
- Once daily
- Estimated price
- $210–420
- Website
- https://www.amtrak.com/home.html
- Website
- flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Raleigh Bus Station to Orlando Bus Station
- Ave. Duration
- 11h 10m
- Frequency
- 5 times a week
- Estimated price
- $95–160
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Fort Pierce
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $28–55
- Website
- https://www.redcoachusa.com
Bus from Kissimmee to Fort Pierce
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $26–50
- Website
- https://www.redcoachusa.com
Bus from Orlando RedCoach Station to Fort Pierce
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $28–55
- Website
- https://www.redcoachusa.com
Bus from Fort Lauderdale Airport to Fort Pierce
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $24–45
- Website
- https://www.redcoachusa.com
- Phone
- (+1) 407 649 4994
- [email protected]
- Website
- miamiorlando.com
Bus from Kissimmee to Fort Pierce
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $30–40
- Website
- https://miamiorlando.com
- Schedules at
- https://miamiorlando.com/schedule.php
- Book at
- https://miamiorlando.com/search-results.php
- Adult
- $30–40
- Ave. Duration
- 45 min
- Estimated price
- $90–110
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