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How to get fromDurham to Port Saint Lucieby plane, taxi, bus (Flixbus), train, bus, car, or bus (Greyhound)

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There are 7 ways to get from Durham to Port Saint Lucie by plane, taxi, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Vero Beach Municipal Airport, taxi

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Vero Beach Municipal Airport (VRB)plane plane RDU - VRB
    2. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    5h 1m
    $169–536

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Raleigh Bus Station to Orlando Bus Stationbus bus FlixBus N2472
    2. Take the bus from Orlando Bus Station to Port St Luciebus bus FlixBus N2401 / ...
    17h 34m
    $120–191

  3. Train, bus

    1. Take the train from Cary to Kissimmee Amtrak Stationtrain train Floridian
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus Orlando to Miami
    19h 27m
    $392–607

  4. Drive  689.8 mi

    1. Drive from Durham to Port Saint Luciecar car 689.8 mi
    12h 4m
    $126–182

  5. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane RDU - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    7h 59m
    $164–490

  6. Fly to Miami International Airport, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Miami International Airport (MIA)plane plane RDU - MIA
    2. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    8h 19m
    $137–752

  7. Bus via Camden

    1. Take the bus from Durham to Camdenbus bus Nyc
    2. Take the bus from Camden to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Port St Luciebus bus
    22h 38m
    $136–216

Durham to Port Saint Lucie by bus (Flixbus)

Calendar5Weekly Buses
Duration17h 34mAverage Duration
Ticket$120Cheapest Price
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Comparing Your Travel Options

Map of how to get from Durham to Port Saint Lucie.ExpandLaunch map view
  • Distance: 620.1 mi
  • Duration: 5h 1m

What companies run services between Durham, NC, USA and Port Saint Lucie, FL, USA?

You can take a bus from Durham to SW PSL Blvd & SE Bayshore Blvd via Raleigh Bus Station, Orlando Bus Station, and SW Gatlin Blvd & SW Brescia St in around 17h 34m.

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