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How to get fromDurham to Sanfordby plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 6 ways to get from Durham to Sanford by plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Raleigh-Durham International Airport to Orlando, train

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Orlando (MCO)plane plane RDU - MCO
    2. Take the train from Sand Lake Road to Sanfordtrain train
    6h 13m
    $79–302

  2. Bus

    1. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus Greyhound US0642S / ...
    2. Take the bus from Fayetteville Bus Station to Deltonabus bus FlixBus N2473
    13h 45m
    $106–182

  3. Train (Amtrak)

    1. Take the train from Cary to Delandtrain train Floridian
    15h 17m
    $188–406

  4. Drive 578.8 mi

    1. Drive from Durham to Sanfordcar car 578.8 mi
    10h 15m
    $106–153

  5. Train to Concord, fly to Orlando Sanford

    1. Take the train from Durham Amtrak Station to Kannapolistrain train
    2. Fly from Concord (USA) to Orlando Sanford (SFB)plane plane USA - SFB
    5h 3m
    $118–324

  6. Train to Charlotte Douglas International Airport, fly to Orlando, train

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Orlando (MCO)plane plane CLT - MCO
    3. Take the train from Sand Lake Road to Sanfordtrain train
    8h 45m
    $158–449

Durham to Sanford by train (Amtrak)

Calendar7Weekly Trains
Duration15h 17mAverage Duration
Ticket$188Cheapest Price
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Questions & Answers

Map of how to get from Durham to Sanford.ExpandLaunch map view
  • Distance: 586.2 mi
  • Duration: 6h 13m

What companies run services between Durham, NC, USA and Sanford, FL, USA?

You can take a bus from Durham to Sanford via Raleigh Bus Station, Fayetteville Bus Station, and Deltona in around 13h 45m. Alternatively, Amtrak operates a train from Cary to Deland once daily. Tickets cost $180–390 and the journey takes 12h 37m.

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