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How to get fromDurham to Senecaby train (Amtrak), bus, taxi, car, plane, or train

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There are 8 ways to get from Durham to Seneca by train (Amtrak), bus, taxi, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train Piedmont / ...
    2. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train Crescent
    7h 2m
    $117–221

  2. Drive 275.7 mi

    cheapest
    1. Drive from Durham to Senecacar car 275.7 mi
    4h 58m
    $51–73

  3. Bus, taxi

    1. Take the bus from Durham to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    3. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    7h 31m
    $165–309

  4. Fly Raleigh-Durham International Airport to Greenville–Spartanburg International Airport, taxi

    1. Fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP)plane plane RDU - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 35m
    $474–726

  5. Bus, train

    1. Take the bus from Durham to Greensboro Bus Stopbus bus Greyhound US0670
    2. Take the train from Greensboro to Clemson Amtrak Stationtrain train Crescent
    7h 42m
    $107–206

  6. Train to Charlotte Douglas International Airport, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Greenville–Spartanburg International Airport (GSP)plane plane CLT - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 47m
    $244–752

  7. Fly Raleigh-Durham International Airport to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Raleigh-Durham International Airport (RDU) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane RDU - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    8h 7m
    $347–828

  8. Train to Charlotte Douglas International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Asheville Regional Airport (AVL)plane plane CLT - AVL
    3. Drive from Asheville-Airport-AVL to Senecacar car
    7h 35m
    $106–441

Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) flights

Calendar114Weekly Planes
Duration3h 59mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Durham to Seneca.ExpandLaunch map view
  • Distance: 292.1 mi
  • Duration: 7h 2m

What companies run services between Durham, NC, USA and Seneca, SC, USA?

You can take a train from Durham Amtrak Station to Seneca via Charlotte Amtrak Station and Clemson Amtrak Station in around 7h 2m.

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