There are 9 ways to get from Durham to West Lafayette by plane, bus (Greyhound, Flixbus), bus, train, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to Purdue University Airport
best- Fly from Raleigh-Durham International Airport (RDU) to Purdue University Airport (LAF)plane RDU - LAF
7h 9m$90–456Bus
cheapest- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
- Take the bus from Columbus to Lafayette Bus Stopbus
18h 14m$84–167Bus, train
- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Ashlandbus
- Take the train from Ashland Amtrak Station to Lafayette Amtrak Stationtrain
19h 7m$124–289Drive 648.9 mi
- Drive from Durham to West Lafayettecar 648.9 mi
11h 32m$119–172Fly Raleigh-Durham International Airport to Indianapolis, bus
- Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane RDU - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
6h 24m$192–416Fly Raleigh-Durham International Airport to Chicago Midway International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane RDU - MDW
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
9h 9m$189–304Train to Charlotte Douglas International Airport, fly to Indianapolis, bus
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane CLT - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
8h 43m$157–679Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane RDU - ORD
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
9h 38m$206–830Train (Amtrak)
- Take the train from Durham Amtrak Station to Greensborotrain
- Take the train from Greensboro to Charlottesvilletrain
- Take the train from Charlottesville to Lafayette Amtrak Stationtrain
23h 55m$224–521
Durham to West Lafayette by bus
Comparing Your Travel Options
The cheapest way to get from Durham to West Lafayette is to bus which costs $80 - $170 and takes 18h 14m.
The fastest way to get from Durham to West Lafayette is to fly and bus which takes 6h 24m and costs $190 - $420.
No, there is no direct bus from Durham to West Lafayette. However, there are services departing from Durham and arriving at Lafayette Bus Stop via Winston Salem(Trans Center), S Grant Ave & E Mound St and Columbus. The journey, including transfers, takes approximately 18h 14m.
No, there is no direct train from Durham station to West Lafayette station. However, there are services departing from Durham Amtrak Station and arriving at Lafayette Amtrak Station via Greensboro and Charlottesville. The journey, including transfers, takes approximately 23h 55m.
The distance between Durham and West Lafayette is 564 miles. The road distance is 652.7 miles.
The best way to get from Durham to West Lafayette without a car is to bus which takes 18h 14m and costs $80 - $170.
It takes approximately 7h 9m to get from Durham to West Lafayette, including transfers.
Durham to West Lafayette bus services, operated by Greyhound USA, depart from Durham station.
Durham to West Lafayette train services, operated by Amtrak, depart from Durham Amtrak Station.
The best way to get from Durham to West Lafayette is to fly which takes 7h 9m and costs $90 - $460. Alternatively, you can bus, which costs $80 - $170 and takes 18h 14m, you could also train, which costs $220 - $550 and takes 23h 55m.
What companies run services between Durham, NC, USA and West Lafayette, IN, USA?
United Airlines and American Airlines fly from Raleigh-Durham International Airport (RDU) to Purdue University Airport (LAF) 3 times a day. Alternatively, you can take a bus from Durham to Lafayette Bus Stop via Winston Salem(Trans Center), Columbus - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 18h 14m.
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Indianapolis via Baltimore
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 2m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $70–400
Flights from Charlotte Douglas International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ashland Amtrak Station to Lafayette Amtrak Station
- Ave. Duration
- 9h 7m
- Frequency
- 3 times a week
- Estimated price
- $85–200
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $30–70
- Website
- Amtrak
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $30–70
- Website
- Amtrak
Train from Durham Amtrak Station to Greensboro
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $14–35
- Website
- Amtrak
Train from Greensboro to Charlottesville
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $40–100
- Website
- Amtrak
Train from Charlottesville to Lafayette Amtrak Station
- Ave. Duration
- 17h 29m
- Frequency
- 3 times a week
- Estimated price
- $170–390
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $12–20
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $12–20
- Website
- Greyhound
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Booking & Getting There
Durham to West Lafayette bus services, operated by Greyhound USA, arrive at Winston Salem(Trans Center) station.
Durham to West Lafayette train services, operated by Amtrak, arrive at Greensboro station.
Yes, the driving distance between Durham to West Lafayette is 653 miles. It takes approximately 11h 32m to drive from Durham to West Lafayette.
Book your Durham to West Lafayette train tickets online with Omio.
Book your Durham to West Lafayette bus tickets online with Omio.
There are 51+ hotels available in West Lafayette.





