Rome2Rio

How to get fromDyer to Mayo Clinicby taxi, train, plane, bus (Greyhound, Flixbus), bus, or car

Find Transport to Mayo Clinic

See all options

There are 8 ways to get from Dyer to Mayo Clinic by taxi, train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the taxi from Dyer to East Chicagotaxi taxi
    2. Take the train from East Chicago to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    5h 48m
    $93–374

  2. Drive  372.7 mi

    cheapest
    1. Drive from Dyer to Mayo Cliniccar car 372.7 mi
    6h 29m
    $68–99

  3. Bus

    1. Take the bus from Gary, IN to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 28m
    $139–191

  4. Train, bus

    1. Take the train from Dyer Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    12h 38m
    $144–307

  5. Taxi, train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the taxi from Dyer to East Chicagotaxi taxi
    2. Take the train from East Chicago to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 25m
    $364–816

  6. Fly Chicago Midway International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 9m
    $179–606

  7. Train, bus via Milwaukee

    1. Take the train from Dyer Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 51m
    $107–177

  8. Train, bus via Madison

    1. Take the train from Dyer Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 20m
    $91–157

Chicago O'Hare International Airport (ORD) to Rochester (RST) flights

Calendar42Weekly Planes
Duration1h 46mAverage Duration
Ticket$41Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Dyer to Mayo Clinic.ExpandLaunch map view
  • Distance: 331.6 mi
  • Duration: 5h 48m

What companies run services between Dyer, IN, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Dyer to Mayo Clinic via Gary, IN, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 10h 28m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound