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How to get fromDyer to Mayo Clinicby train, plane, bus (Greyhound, Flixbus), bus, or car

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There are 8 ways to get from Dyer to Mayo Clinic by train, plane, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from Munster Dyer Station to Hammond Gatewaytrain train
    2. Take the train from Hammond Gateway to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    5h 56m
    $67–353

  2. Bus

    1. Take the bus from Gary, IN to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 28m
    $139–191

  3. Train, bus

    1. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train Borealis / ...
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    12h 34m
    $154–313

  4. Drive  372.7 mi

    1. Drive from Dyer to Mayo Cliniccar car 372.7 mi
    6h 29m
    $68–99

  5. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Hammond Gateway to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 34m
    $318–785

  6. Fly Chicago Midway International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 23m
    $153–585

  7. Train, bus via Milwaukee

    1. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    2. Take the bus from Milwaukee to Rochesterbus bus Jefferson Lines 966
    10h 47m
    $117–181

  8. Train, bus via Madison

    1. Take the train from Dyer Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 20m
    $91–157

Chicago O'Hare International Airport (ORD) to Rochester (RST) flights

Calendar35Weekly Planes
Duration1h 49mAverage Duration
Ticket$40Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Dyer to Mayo Clinic.ExpandLaunch map view
  • Distance: 324.4 mi
  • Duration: 5h 56m

What companies run services between Dyer, IN, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Dyer to Mayo Clinic via Gary, IN, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 10h 28m.

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Bus operators

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