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How to get fromEast Harlem to Buffaloby bus, plane, train (Amtrak), car, subway, train, or bus (Flixbus)

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There are 9 ways to get from East Harlem to Buffalo by bus, plane, train (Amtrak), car, subway, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    3h 53m
    $100–686

  2. Bus

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816 / ...
    9h 15m
    $63–283

  3. Train via Yonkers

    1. Take the train from Yonkers Amtrak Station to Buffalotrain train Empire Service / ...
    9h 22m
    $117–291

  4. Drive 362.6 mi

    1. Drive from East Harlem to Buffalocar car 362.6 mi
    7h 17m
    $67–96

  5. Line 6 subway, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 110th Street to Grand Central-42 Stsubway subway
    2. Take the train from Grand Central Terminal to Jamaicatrain train
    3. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 9m
    $94–530

  6. Subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 96 St to 34 St-Herald Sqsubway subway
    2. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 23m
    $100–550

  7. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 31m
    $122–652

  8. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 37m
    $113–293

  9. Bus via New York Midtown (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    9h 43m
    $73–123

East Harlem to Buffalo by subway, foot, and bus

Calendar45Weekly Services
Duration9h 15mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from East Harlem to Buffalo.ExpandLaunch map view
  • Distance: 312.5 mi
  • Duration: 3h 53m

What companies run services between East Harlem, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Alternatively, Amtrak operates a train from Yonkers Amtrak Station to Buffalo twice daily. Tickets cost $130–280 and the journey takes 7h 58m. VIA Rail also services this route once daily.

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