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How to get fromEast Lansing to Knoxvilleby plane, bus (Amtrak, Flixbus), car, bus, bus (Greyhound), or train

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There are 7 ways to get from East Lansing to Knoxville by plane, bus (Amtrak, Flixbus), car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Capital Region International Airport

    best
    1. Fly from Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS)plane plane LAN - TYS
    5h 4m
    $221–900

  2. Drive 523.2 mi

    cheapest
    1. Drive from East Lansing to Knoxvillecar car 523.2 mi
    9h 53m
    $96–138

  3. Bus

    1. Take the bus from East Lansing Amtrak Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    31h 25m
    $339–519

  4. Bus to Detroit, fly

    1. Take the bus from East Lansing Marriott to DTW McNamara Terminalbus bus
    2. Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane plane DTW - TYS
    4h 58m
    $185–850

  5. Bus via Detroit

    1. Take the bus from East Lansing Michigan Flyer to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    33h 12m
    $313–512

  6. Bus, train via Farragut

    1. Take the bus from East Lansing Amtrak Station to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    34h 28m
    $469–819

  7. Bus, train

    1. Take the bus from East Lansing Amtrak Station to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    34h 32m
    $424–729

Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS) flights

Calendar40Weekly Planes
Duration5h 27mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from East Lansing to Knoxville.ExpandLaunch map view
  • Distance: 502.2 mi
  • Duration: 5h 4m

What companies run services between East Lansing, MI, USA and Knoxville, TN, USA?

American Airlines, Delta, and United Airlines fly from Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from WBD Gr. River past MAC AVE to Knoxville via East Lansing Amtrak Station, Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 31h 25m.

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