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How to get fromEast Los Angeles to Otay Mesaby bus, train (Amtrak), car, tram, plane, or bus (Flixbus)

Find Transport to Otay Mesa

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There are 5 ways to get from East Los Angeles to Otay Mesa by bus, train (Amtrak), car, tram, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Downtown Los Angeles to San Ysidro, CAbus bus Las Vegas / ...
    5h 21m
    $46–77
  2. Drive 131.3 mi

    cheapest
    1. Drive from East Los Angeles to Otay Mesacar car 131.3 mi
    2h 20m
    $24–35
  3. Train (Amtrak)

    1. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    5h 31m
    $41–104
  4. Tram, fly, line 905 bus

    1. Take the tram from Maravilla Station to Little Tokyo / Arts District Stationtram tram
    2. Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane plane LAX - SAN
    3. Take the tram from Civic Center Station to Iris Avenue Stationtram tram
    4. Take the bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rdbus bus
    5h 1m
    $175–589
  5. Bus via Old Town Station (Flixbus)

    1. Take the bus from Los Angeles Downtown to San Diegobus bus FlixBus 2006 / ...
    6h 37m
    $25–54

East Los Angeles to Otay Mesa by bus and foot

Calendar21Weekly Services
Duration5h 21mAverage Duration
Ticket$46Cheapest Price
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Questions & Answers

What companies run services between East Los Angeles, CA, USA and Otay Mesa, CA, USA?

Tufesa operates a bus from Downtown Los Angeles to San Ysidro, CA 3 times a day. Tickets cost $40–65 and the journey takes 2h 45m. Alternatively, Amtrak operates a train from Los Angeles to San Diego Old Town Transportation Center hourly. Tickets cost $35–85 and the journey takes 2h 42m.

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