There are 5 ways to get from East Los Angeles to Otay Mesa by bus, train (Amtrak), car, tram, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Downtown Los Angeles to San Ysidro, CAbus Las Vegas / ...
5h 21m$46–77Drive 131.3 mi
cheapest- Drive from East Los Angeles to Otay Mesacar 131.3 mi
2h 20m$24–35Train (Amtrak)
- Take the train from Los Angeles to San Diego Old Town Transportation Centertrain Pacific Surfliner
5h 31m$41–104Tram, fly, line 905 bus
- Take the tram from Maravilla Station to Little Tokyo / Arts District Stationtram
- Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane LAX - SAN
- Take the tram from Civic Center Station to Iris Avenue Stationtram
- Take the bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rdbus
5h 1m$175–589Bus via Old Town Station (Flixbus)
- Take the bus from Los Angeles Downtown to San Diegobus FlixBus 2006 / ...
6h 37m$25–54
East Los Angeles to Otay Mesa by bus and foot
Questions & Answers
The cheapest way to get from East Los Angeles to Otay Mesa is to drive which costs $24 - $35 and takes 2h 20m.
The fastest way to get from East Los Angeles to Otay Mesa is to drive which takes 2h 20m and costs $24 - $35.
No, there is no direct bus from East Los Angeles to Otay Mesa. However, there are services departing from Whittier / Eastern and arriving at Otay Mesa Rd & Cactus Rd via Downtown Los Angeles, San Ysidro Transit Center and Iris Avenue Transit Center. The journey, including transfers, takes approximately 5h 21m.
No, there is no direct train from East Los Angeles to Otay Mesa station. However, there are services departing from Los Angeles and arriving at Iris Avenue Station via Old Town Station. The journey, including transfers, takes approximately 5h 31m.
The distance between East Los Angeles and Otay Mesa is 150 miles. The road distance is 132.1 miles.
The best way to get from East Los Angeles to Otay Mesa without a car is to bus which takes 5h 21m and costs $45 - $80.
It takes approximately 5h 21m to get from East Los Angeles to Otay Mesa, including transfers.
East Los Angeles to Otay Mesa bus services, operated by Tufesa, depart from Downtown Los Angeles station.
East Los Angeles to Otay Mesa train services, operated by Amtrak, depart from Los Angeles station.
The best way to get from East Los Angeles to Otay Mesa is to bus which takes 5h 21m and costs $45 - $80. Alternatively, you can train, which costs $40 - $110 and takes 5h 31m.
What companies run services between East Los Angeles, CA, USA and Otay Mesa, CA, USA?
Tufesa operates a bus from Downtown Los Angeles to San Ysidro, CA 3 times a day. Tickets cost $40–65 and the journey takes 2h 45m. Alternatively, Amtrak operates a train from Los Angeles to San Diego Old Town Transportation Center hourly. Tickets cost $35–85 and the journey takes 2h 42m.
- Website
- delta.com
Flights from Los Angeles International Airport to San Diego International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $30–260
- Website
- united.com
Flights from Los Angeles International Airport to San Diego International Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- $30–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- $35–85
- Website
- Amtrak
- Phone
- +1-323-466-3876
- [email protected]
- Website
- Metro Los Angeles
Tram from Maravilla Station to Little Tokyo / Arts District Station
- Ave. Duration
- 13 min
- Frequency
- Every 15 minutes
- Estimated price
- $2
- Website
- Metro Los Angeles
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Civic Center Station to Iris Avenue Station
- Ave. Duration
- 36 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–14
- Website
- MTS
- Schedules at
- MTS Schedules
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from Downtown Los Angeles to San Ysidro, CA
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Schedules at
- Tufesa
- Adult One way
- $40–65
- Phone
- +1 619-557-4555
- Website
- MTS
Bus from Iris Avenue Transit Center to Otay Mesa Rd & Cactus Rd
- Ave. Duration
- 11 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- MTS
- Schedules at
- MTS Schedules
- One Way - Adult/Youth
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Downtown to San Diego
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $19–35
- Schedules at
- Flixbus USA
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More Questions & Answers
East Los Angeles to Otay Mesa bus services, operated by Tufesa, arrive at San Ysidro, CA station.
East Los Angeles to Otay Mesa train services, operated by Amtrak, arrive at San Diego Old Town Transportation Center station.
Yes, the driving distance between East Los Angeles to Otay Mesa is 132 miles. It takes approximately 2h 20m to drive from East Los Angeles to Otay Mesa.
There are 561+ hotels available in Otay Mesa.
















