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How to get fromEast Saint Louis to Milwaukeeby plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or train

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There are 6 ways to get from East Saint Louis to Milwaukee by plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    3h 30m
    $486–856

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150 / ...
    9h 52m
    $66–118

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    8h 34m
    $120–252

  4. Drive 366 mi

    1. Drive from East Saint Louis to Milwaukeecar car 366 mi
    6h 18m
    $67–97

  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    5h 51m
    $310–798

  6. Train, bus

    1. Take the train from St. Louis to Summit Amtraktrain train Lincoln Service / ...
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus Wisconsin Coach Lines
    9h 29m
    $126–228

East Saint Louis to Milwaukee by train (Amtrak)

Calendar38Weekly Trains
Duration8h 34mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from East Saint Louis to Milwaukee.ExpandLaunch map view
  • Distance: 343 mi
  • Duration: 3h 30m

What companies run services between East Saint Louis, IL, USA and Milwaukee, WI, USA?

Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) twice daily. Alternatively, you can take a train from 5TH & MISSOURI station to Milwaukee via CIVIC CENTER station, St. Louis, and Chicago Union Station in around 8h 34m.

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