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How to get fromEast Setauket to Chicagoby train, plane, train (Amtrak), bus (Flixbus), car, car ferry, or bus

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There are 11 ways to get from East Setauket to Chicago by train, plane, train (Amtrak), bus (Flixbus), car, car ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to John F. Kennedy International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Chicago O'Hare International Airport (ORD)plane plane JFK - ORD
    6h 56m
    $375–893

  2. Train to Westchester County Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from Westchester County Airport (HPN) to Chicago O'Hare International Airport (ORD)plane plane HPN - ORD
    9h 39m
    $140–708

  3. Train

    1. Take the train from Ronkonkoma to New York Penn Stationtrain train Ronkonkoma Branch
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    22h 53m
    $515–882

  4. Bus

    1. Take the bus from Manorville to 86 St & Central Park Westbus bus Sag Harbor-Westbound / ...
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus FlixBus N2640 / ...
    26h 12m
    $213–395

  5. Drive  844.2 mi

    1. Drive from East Setauket to Chicagocar car 844.2 mi
    14h 20m
    $145–209

  6. Train to Laguardia Airport, fly to Chicago Midway International Airport

    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Chicago Midway International Airport (MDW)plane plane LGA - MDW
    7h 14m
    $221–699

  7. Train to Laguardia Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Chicago O'Hare International Airport (ORD)plane plane LGA - ORD
    7h 32m
    $141–509

  8. Train to Newark Liberty International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Chicago O'Hare International Airport (ORD)plane plane EWR - ORD
    7h 40m
    $150–669

  9. Car ferry, train to Bradley International Airport, fly to Chicago Midway International Airport

    1. Take the carferry from Port Jefferson to Bridgeportcarferry car ferry
    2. Take the train from New Haven to Hartford Amtrak Stationtrain train
    3. Fly from Bradley International Airport (BDL) to Chicago Midway International Airport (MDW)plane plane BDL - MDW
    9h 36m
    $152–688

  10. Train to Laguardia Airport, fly to General Mitchell International Airport, train

    1. Take the train from Stony Brook to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to General Mitchell International Airport (MKE)plane plane LGA - MKE
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    9h 48m
    $206–883

  11. Train, bus

    1. Take the train from Ronkonkoma to New York Penn Stationtrain train
    2. Take the bus from New York to Baltimorebus bus
    3. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    26h 49m
    $190–317

East Setauket to Chicago by bus and train

Calendar10Weekly Services
Duration22h 53mAverage Duration
Ticket$515Cheapest Price
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Comparing Your Travel Options

Map of how to get from East Setauket to Chicago.ExpandLaunch map view
  • Distance: 806.6 mi
  • Duration: 6h 56m

What companies run services between East Setauket, NY, USA and Chicago, IL, USA?

You can take a bus from NYS 25A/Main St to Chicago Union Station via Ronkonkoma LIRR, Ronkonkoma, Penn Station, and Ny Moynihan Train Hall At Penn Station in around 22h 53m. Alternatively, you can take a bus from NYS 25A/Main St to Chicago Bus Station via Ronkonkoma LIRR, Islip Airport Connection, Manorville, 86 St & Central Park West, 86 St, 34 St-Herald Sq, and New York Midtown in around 26h 12m.

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