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How to get fromEcuador to Santa Cruzby plane, bus, or car

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There are 5 ways to get from Ecuador to Santa Cruz by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from José Joaquín De Olmedo International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI)plane plane GYE - VVI
    7h 36m
    $456–719

  2. Bus via Máncora

    cheapest
    1. Take the bus from Guayaquil to Máncorabus bus
    2. Take the bus from Máncora to Lima 28 de Juliobus bus
    3. Take the bus from Oltursa Lima Terminal to La Pazbus bus
    4. Take the bus from La Paz to Santa Cruzbus bus
    3d 13h
    $161–242

  3. Bus

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Plaza Nortebus bus
    2. Take the bus from Lima - Terminal Arriola to La Pazbus bus
    3. Take the bus from La Paz to Santa Cruzbus bus
    3d 7h
    $166–722

  4. Drive  3,717.3 km

    1. Drive from Guayaquil to Santa Cruz de la Sierracar car 3,717.3 km
    2d 4h
    $211–305

  5. Car to Mariscal Sucre International Airport, fly

    1. Drive from Quito to Quito Airportcar car
    2. Fly from Mariscal Sucre International Airport (UIO) to Viru Viru International Airport (VVI)plane plane UIO - VVI
    9h 35m
    $486–776

José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI) flights

Calendar23Weekly Planes
Duration9h 49mAverage Duration
Ticket$201Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ecuador to Santa Cruz.ExpandLaunch map view
  • Distance: 2,545 km
  • Duration: 7h 36m

What companies run services between Ecuador and Santa Cruz, Bolivia?

LATAM Chile, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI) 3 times a day. Alternatively, you can take a vehicle from Guayaquil to Santa Cruz de la Sierra via Terminal Terrestre de Guayaquil, Lima Plaza Norte, Municipalidad Del Rímac, Óvalo Arriola, Lima - Terminal Arriola, La Paz, and Santa Cruz in around 3d 7h.

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