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How to get fromEcuador to Santiagoby plane, bus, or car

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There are 5 ways to get from Ecuador to Santiago by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from José Joaquín De Olmedo International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane GYE - SCL
    5h 28m
    $254–568

  2. Bus

    cheapest
    1. Take the bus from Guayaquil to Duránbus bus
    2. Take the bus from Durán to Terminal Terrestre de Guayaquilbus bus
    3. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    4. Take the bus from Lima Javier Prado to Terminal Sur de Santiagobus bus
    3d 9h
    $153–309

  3. Bus via Tumbes

    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Gran Terminal Terrestre Plaza Norte to Terminal San Borjabus bus
    2d 19h
    $274–348

  4. Drive 4,689.6 km

    1. Drive from Guayaquil to Santiagocar car 4,689.6 km
    2d 12h
    $579–836

  5. Fly from Cuenca

    1. Fly from Cuenca (CUE) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane CUE - SCL
    11h 49m
    $234–428

José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

Calendar45Weekly Planes
Duration7h 29mAverage Duration
Ticket$238Cheapest Price
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Questions & Answers

Map of how to get from Ecuador to Santiago.ExpandLaunch map view
  • Distance: 3,626.5 km
  • Duration: 5h 28m

What companies run services between Ecuador and Santiago, Chile?

LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL) every 4 hours. Alternatively, you can take a vehicle from Guayaquil to Terminal San Borja via Terminal Terrestre de Guayaquil, Tumbes, Tumbes, and Gran Terminal Terrestre Plaza Norte in around 2d 19h.

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