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How to get fromEcuador to Santiagoby plane, bus, or car

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There are 6 ways to get from Ecuador to Santiago by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from José Joaquín De Olmedo International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane GYE - SCL
    5h 30m
    $236–621

  2. Bus

    cheapest
    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus Lima
    2. Take the bus from Lima Javier Prado to Terminal Sur de Santiagobus bus Lima
    3d 12h
    $153–285

  3. Bus via Tumbes

    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Lima Terminal Exclucivabus bus
    3. Take the bus from Lima Javier Prado to Terminal Sur de Santiagobus bus
    3d 7h
    $173–290

  4. Drive  4,710.8 km

    1. Drive from Guayaquil to Santiagocar car 4,710.8 km
    2d 13h
    $581–839

  5. Car to Mariscal Sucre International Airport, fly

    1. Drive from Quito to Quito Airportcar car
    2. Fly from Mariscal Sucre International Airport (UIO) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane UIO - SCL
    7h 42m
    $256–438

  6. Bus #2

    1. Take the bus from Guayaquil to Máncorabus bus
    2. Take the bus from Máncora to Lima Javier Pradobus bus
    3. Take the bus from Lima Javier Prado to Terminal Sur de Santiagobus bus
    3d 20h
    $173–264

José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

Calendar25Weekly Planes
Duration7h 32mAverage Duration
Ticket$221Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ecuador to Santiago.ExpandLaunch map view
  • Distance: 3,626.5 km
  • Duration: 5h 30m

What companies run services between Ecuador and Santiago, Chile?

LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Comodoro Arturo Merino Benítez International Airport (SCL) 4 times a day. Alternatively, you can take a vehicle from Guayaquil to Terminal Sur de Santiago via Terminal Terrestre de Guayaquil, Tumbes, Tumbes, Lima Terminal Excluciva, and Lima Javier Prado in around 3d 7h.

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