There are 4 ways to get from Edwardsville to Des Moines by taxi, plane, bus (Greyhound), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, fly
best- Take the taxi from Edwardsville to St-Louis-Airport-STLtaxi
- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
4h 7m$226–853Drive 327.2 mi
cheapest- Drive from Edwardsville to Des Moinescar 327.2 mi
7h 22m$60–87Bus (Greyhound)
- Take the bus from St Louis Bus Station to Des Moinesbus Greyhound US0153S
8h 55m$119–193Train, bus
- Take the train from Alton Station to Bloomington-Normaltrain Texas Eagle / ...
- Take the bus from Bloomington-Normal to Des Moinesbus Greyhound US0157S
9h 48m$120–221
Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Edwardsville to Des Moines is to drive which costs $55 - $90 and takes 7h 22m.
The fastest way to get from Edwardsville to Des Moines is to taxi and fly which takes 4h 7m and costs $220 - $900.
No, there is no direct bus from Edwardsville station to Des Moines. However, there are services departing from St Louis Bus Station and arriving at Des Moines via . The journey, including transfers, takes approximately 8h 55m.
The distance between Edwardsville and Des Moines is 296 miles. The road distance is 329.1 miles.
The best way to get from Edwardsville to Des Moines without a car is to bus which takes 8h 55m and costs $110 - $200.
It takes approximately 4h 7m to get from Edwardsville to Des Moines, including transfers.
Edwardsville to Des Moines bus services, operated by Greyhound USA, depart from St Louis Bus Station.
Edwardsville to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Edwardsville to Des Moines is 329 miles. It takes approximately 7h 22m to drive from Edwardsville to Des Moines.
There are 241+ hotels available in Des Moines.
What companies run services between Edwardsville, IL, USA and Des Moines, IA, USA?
Greyhound USA operates a bus from St Louis Bus Station to Des Moines once daily. Tickets cost $65–130 and the journey takes 8h 25m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $240–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 32m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 15m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $260–1,200
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Lambert–St. Louis International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Alton Station to Bloomington-Normal
- Ave. Duration
- 1h 49m
- Frequency
- 5 times a day
- Estimated price
- $40–90
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Bloomington-Normal to Des Moines
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Ave. Duration
- 35 min
- Estimated price
- $65–85
Chesterfield Taxi
- Phone
- +1 314-734-0100
- Website
- chesterfieldtaxi.com
On Time Cab Service
- Phone
- +1-314-606-9679
- Website
- ontimecabservice.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide








