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How to get fromEdwardsville to Knoxvilleby taxi, plane, train, bus, car, or bus (Greyhound)

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There are 5 ways to get from Edwardsville to Knoxville by taxi, plane, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Edwardsville to St-Louis-Airport-STLtaxi taxi
    2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    3. Take the taxi from Des-Moines-Airport-DSM to Knoxvilletaxi taxi
    4h 46m
    $279–982

  2. Drive 292.7 mi

    cheapest
    1. Drive from Edwardsville to Knoxvillecar car 292.7 mi
    6h 47m
    $54–78

  3. Train, bus

    1. Take the train from Alton Station to Bloomington-Normaltrain train Texas Eagle / ...
    2. Take the bus from Bloomington-Normal to Oskaloosabus bus Greyhound US0157S
    9h 4m
    $160–266

  4. Train, bus via Galesburg

    1. Take the train from Alton Station to Springfieldtrain train
    2. Take the bus from Springfield to Galesburg Amtrak Stationbus bus
    3. Take the bus from Galesburg to Monroebus bus
    10h 6m
    $153–246

  5. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    2. Take the bus from Des Moines to Monroebus bus Greyhound US0157S
    11h 3m
    $153–237

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

Calendar133Weekly Planes
Duration4h 45mAverage Duration
Ticket$136Cheapest Price
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Questions & Answers

Map of how to get from Edwardsville to Knoxville.ExpandLaunch map view
  • Distance: 323.9 mi
  • Duration: 4h 46m

What companies run services between Edwardsville, IL, USA and Knoxville, IA, USA?

You can take a vehicle from Edwardsville to Knoxville via St Louis Bus Station, Des Moines, and Monroe in around 11h 3m.

Airlines
Train operators
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