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How to get fromEffingham to Great Smoky Mountainsby bus, plane, car, or train

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There are 8 ways to get from Effingham to Great Smoky Mountains by bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the bus from Effingham to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 8m
    $148–798

  2. Drive 472.4 mi

    cheapest
    1. Drive from Effingham to Great Smoky Mountainscar car 472.4 mi
    10h 10m
    $87–125

  3. Bus, drive (Greyhound)

    1. Take the bus from Effingham to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    23h 33m
    $144–278

  4. Bus, train, drive

    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    29h 36m
    $306–631

  5. Train to University Of Illinois Willard Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Effingham Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS)plane plane CMI - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    8h 42m
    $171–735

  6. Bus to Lambert–St. Louis International Airport, fly to Nashville, drive

    1. Take the bus from Effingham to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    3. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    9h 6m
    $138–697

  7. Train, bus to Decatur Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Effingham Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Mcghee Tyson Airport (TYS)plane plane DEC - TYS
    4. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    12h 56m
    $174–793

  8. Bus, train, drive via Ironville

    1. Take the bus from Effingham to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    23h 33m
    $187–376

Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) flights

Calendar113Weekly Planes
Duration5h 2mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Effingham to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 578.7 mi
  • Duration: 9h 8m

What companies run services between Effingham, IL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Effingham to Great Smoky Mountains. However, you can take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Effingham to Great Smoky Mountains via Columbus, Winston Salem(Trans Center), and Asheville, NC in around 23h 33m.

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