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How to get fromEffingham to Greenvilleby bus, plane, train, car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Effingham to Greenville by bus, plane, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the bus from Effingham to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    6h 46m
    $173–777

  2. Drive 562.4 mi

    cheapest
    1. Drive from Effingham to Greenvillecar car 562.4 mi
    12h 11m
    $103–149

  3. Train, bus

    1. Take the train from Effingham Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    16h 8m
    $168–364

  4. Train, bus to Decatur Airport, fly

    1. Take the train from Effingham Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Greenville–Spartanburg International Airport (GSP)plane plane DEC - GSP
    11h 26m
    $189–722

  5. Bus

    1. Take the bus from Effingham to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    19h 48m
    $161–364

Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) flights

Calendar126Weekly Planes
Duration4h 44mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Effingham to Greenville.ExpandLaunch map view
  • Distance: 650 mi
  • Duration: 6h 46m

What companies run services between Effingham, IL, USA and Greenville, SC, USA?

You can take a bus from Effingham to Greenville via St Louis Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 19h 48m.

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