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How to get fromElkhart to Mayo Clinicby plane, bus (Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Elkhart to Mayo Clinic by plane, bus (Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly South Bend to Rochester

    best
    1. Fly from South Bend (SBN) to Rochester (RST)plane plane SBN - RST
    5h 36m
    $109–438

  2. Drive  450.9 mi

    cheapest
    1. Drive from Elkhart to Mayo Cliniccar car 450.9 mi
    7h 50m
    $78–112

  3. Bus

    1. Take the bus from Elkhart Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h

  4. Train, bus

    1. Take the train from Elkhart Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 18m
    $303–474

  5. Fly South Bend to Minneapolis–Saint Paul International Airport, bus

    1. Fly from South Bend (SBN) to Minneapolis–Saint Paul International Airport (MSP)plane plane SBN - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 25m
    $178–558

  6. Train to Chicago O'Hare International Airport, fly to Rochester

    1. Take the train from Elkhart Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    7h 2m
    $96–392

  7. Train, bus via Madison

    1. Take the train from Elkhart Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h
    $130–214

  8. Bus via South Bend

    1. Take the bus from South Bend to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    13h 50m
    $92–151

South Bend (SBN) to Rochester (RST) flights

Calendar37Weekly Planes
Duration6h 10mAverage Duration
Ticket$53Cheapest Price
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Comparing Your Travel Options

Map of how to get from Elkhart to Mayo Clinic.ExpandLaunch map view
  • Distance: 376 mi
  • Duration: 5h 36m

What companies run services between Elkhart, IN, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from South Bend (SBN) to Rochester (RST) 5 times a day. Alternatively, you can take a bus from Elkhart Amtrak Station to Mayo Clinic via Chicago Union Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 12h.

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