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How to get fromEnschede to Madridby train, plane, train (Eurostar, TGV, Renfe, Ouigo), bus, car, or train (Eurostar, TGV, Renfe)

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There are 11 ways to get from Enschede to Madrid by train, plane, train (Eurostar, TGV, Renfe, Ouigo), bus, car, or train (Eurostar, TGV, Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, train to Amsterdam Airport Schiphol, fly

    best
    1. Take the train from Enschede to Amersfoort Centraaltrain train
    2. Take the train from Amersfoort Centraal to Schiphol Airport Train Stationtrain train
    3. Fly from Amsterdam Airport Schiphol (AMS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane AMS - MAD
    7h 16m
    €94–300

  2. Train to Münster Osnabrück International Airport, fly

    cheapest
    1. Take the train from Enschede to Muenster(Westf)Hbftrain train
    2. Fly from Münster Osnabrück International Airport (FMO) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FMO - MAD
    9h 25m
    €87–409

  3. Train via Barcelona

    1. Take the train from Enschede to Goudatrain train
    2. Take the train from Rotterdam Centraal to Marne La Vallee Chessytrain train
    3. Take the train from Marne La Vallee Chessy to Perpignantrain train Tgv
    4. Take the train from Perpignan to Barcelona-Santstrain train Tgv
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    18h 32m
    €424–789

  4. Bus

    1. Take the bus from Enschede to Brussels-North train stationbus bus N81
    2. Take the bus from Brussels-North train station to Madridbus bus FlixBus N1143
    28h 20m
    €155–237

  5. Drive  1,830.9 km

    1. Drive from Enschede to Madridcar car 1,830.9 km
    18h 26m
    €337–487

  6. Train, train to Düsseldorf International Airport, fly

    1. Take the train from Enschede to Duelmentrain train
    2. Take the train from Dülmen, Bahnhof to D-Flughafen Bftrain train
    3. Fly from Düsseldorf International Airport (DUS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane DUS - MAD
    7h 59m
    €99–350

  7. Train, train to Brussels Airport, fly

    1. Take the train from Enschede to Deventertrain train
    2. Take the train from Deventer to Bredatrain train
    3. Take the train from Breda to Brussels Airport-Zaventemtrain train
    4. Fly from Brussels Airport (BRU) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane BRU - MAD
    9h 18m
    €94–296

  8. Train, train to Frankfurt, fly

    1. Take the train from Enschede to Muenster(Westf)Hbftrain train
    2. Take the train from Münster Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane FRA - MAD
    9h 42m
    €143–410

  9. Train, bus via Lyon

    1. Take the train from Enschede to Utrecht Centraaltrain train
    2. Take the bus from Utrecht to Lille - Europe Train Stationbus bus
    3. Take the train from Lille Europe to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    18h 51m
    €271–598

  10. Train

    1. Take the train from Enschede to Rotterdam Centraaltrain train
    2. Take the train from Rotterdam Centraal to Paris Nordtrain train
    3. Take the train from Paris Montparnasse 1 Et 2 to Hendayetrain train Tgv
    4. Take the train from Irun to Madrid Chamartíntrain train Alv / ...
    20h 5m
    €386–652

  11. Train, bus

    1. Take the train from Enschede to Dortmund Hbftrain train Re
    2. Take the train from Dortmund Hbf to Frankfurttrain train 41 / ...
    3. Take the bus from Frankfurt - Main Bus Station to Estación Sur de Autobusesbus bus
    35h 11m
    €197–418

Enschede to Madrid by train

Calendar4Weekly Trains
Duration18h 32mAverage Duration
Ticket€424Cheapest Price
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Comparing Your Travel Options

Map of how to get from Enschede to Madrid.ExpandLaunch map view
  • Distance: 1,642.2 km
  • Duration: 7h 16m

What companies run services between Enschede, Netherlands and Madrid, Spain?

You can take a train from Enschede to Madrid-Puerta de Atocha-Almudena Grandes via Gouda, Rotterdam Centraal, Marne La Vallee Chessy, Perpignan, and Barcelona-Sants in around 18h 32m. Alternatively, you can take a bus from Enschede to Madrid via Brussels-North train station in around 28h 20m.

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