Rome2Rio

How to get fromEnschede to Sienaby train, plane, train (Trenitalia), bus, night train, car, or car train

Find Transport to Siena

See all options

There are 13 ways to get from Enschede to Siena by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, train to Düsseldorf International Airport, fly to Florence Peretola Airport

    best
    1. Take the train from Enschede to Dülmen, Bahnhoftrain train
    2. Take the train from Dülmen, Bahnhof to D-Flughafen Bftrain train
    3. Fly from Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR)plane plane DUS - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 27m
    €138–367

  2. Train, train to Cologne Bonn Airport, fly to Bologna Guglielmo Marconi Airport

    cheapest
    1. Take the train from Enschede to Münster Hauptbahnhoftrain train
    2. Take the train from Münster Hauptbahnhof to Köln Hbftrain train
    3. Fly from Cologne Bonn Airport (CGN) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CGN - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    10h 32m
    €101–390

  3. Train

    1. Take the train from Enschede to Münster Hauptbahnhoftrain train
    2. Take the train from Münster Hauptbahnhof to Basel SBBtrain train 43
    3. Take the train from Basel SBB to Luganotrain train Ec
    4. Take the train from Lugano to Milano Centraletrain train
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 22m
    €206–586

  4. Bus

    1. Take the bus from Enschede to Dortmund central bus stationbus bus
    2. Take the bus from Dortmund Hbf to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    22h 40m
    €167–246

  5. Train, night train, bus

    1. Take the train from Enschede to Dortmund Hbftrain train
    2. Take the train from Dortmund Hbf to München Hbftrain train 47 / ...
    3. Take the nighttrain from Muenchen Hbf to Firenze Campo Martenighttrain night train Nj
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    22h 33m
    €138–477

  6. Train to Münster Osnabrück International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Enschede to Münster Hauptbahnhoftrain train
    2. Fly from Münster Osnabrück International Airport (FMO) to Florence Peretola Airport (FLR)plane plane FMO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    10h 9m
    €219–497

  7. Train, train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport

    1. Take the train from Enschede to Amersfoort Centraaltrain train
    2. Take the train from Amersfoort Centraal to Schiphol Airport Train Stationtrain train
    3. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane plane AMS - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 4m
    €131–295

  8. Train, train to Amsterdam Airport Schiphol, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Enschede to Amersfoort Centraaltrain train
    2. Take the train from Amersfoort Centraal to Schiphol Airport Train Stationtrain train
    3. Fly from Amsterdam Airport Schiphol (AMS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane AMS - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    9h 37m
    €128–325

  9. Train, train to Eindhoven Airport, fly to Pisa International Airport

    1. Take the train from Enschede to Utrecht Centraaltrain train
    2. Take the train from Utrecht Centraal to Eindhoven Centraaltrain train
    3. Fly from Eindhoven Airport (EIN) to Pisa International Airport (PSA)plane plane EIN - PSA
    4. Take the train from Pisa Centrale to Empolitrain train
    5. Take the train from Empoli to Sienatrain train
    9h 27m
    €101–350

  10. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Enschede to Münster Hauptbahnhoftrain train
    2. Take the train from Münster Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    11h 29m
    €172–468

  11. Train, bus

    1. Take the train from Enschede to Dortmund Hbftrain train
    2. Take the bus from Dortmund central bus station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    24h 38m
    €127–259

  12. Drive  1,341.7 km

    1. Drive from Enschede to Sienacar car 1,341.7 km
    12h 36m
    €248–358

  13. Drive, car train

    1. Drive from Enschede to Fuldacar car
    2. Take the cartrain from Fulda to München Ostcartrain train
    3. Drive from München Ost to Sienacar car
    15h 23m
    €266–358

Enschede to Siena by train

Calendar76Weekly Trains
Duration18h 22mAverage Duration
Ticket€206Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Enschede to Siena.ExpandLaunch map view
  • Distance: 1,144.4 km
  • Duration: 9h 27m

What companies run services between Enschede, Netherlands and Siena, Italy?

You can take a train from Enschede to Siena via Münster Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 18h 22m. Alternatively, you can take a bus from Enschede to Siena via Dortmund central bus station, Dortmund Hbf, and Florence Villa Constanza Bus Station in around 22h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There