Rome2Rio

How to get fromErie to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Find Transport to La Crosse

See all options

There are 7 ways to get from Erie to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Erie International Airport

    best
    1. Fly from Erie International Airport (ERI) to La Crosse (LSE)plane plane ERI - LSE
    6h 54m
    $86–405

  2. Train (Amtrak)

    1. Take the train from Erie Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    14h 55m
    $389–606

  3. Bus

    1. Take the bus from Erie to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    17h 40m
    $136–216

  4. Drive  723.8 mi

    1. Drive from Erie to La Crossecar car 723.8 mi
    12h 11m
    $133–191

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to La Crosse (LSE)plane plane CLE - LSE
    7h 44m
    $149–556

  6. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Erie to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to La Crosse (LSE)plane plane BUF - LSE
    9h 9m
    $112–494

  7. Train, bus

    1. Take the train from Erie Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    16h 33m
    $299–476

Erie to La Crosse by train (Amtrak)

Calendar14Weekly Trains
Duration14h 55mAverage Duration
Ticket$389Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Erie to La Crosse.ExpandLaunch map view
  • Distance: 595.2 mi
  • Duration: 6h 54m

What companies run services between Erie, PA, USA and La Crosse, WI, USA?

American Airlines flies from Erie International Airport (ERI) to La Crosse (LSE) once daily. Alternatively, you can take a train from Erie Station to La Crosse Amtrak Station via Chicago Union Station in around 14h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There