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How to get fromErie to Louisvilleby bus (Flixbus, Greyhound), car, plane, train, or bus

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There are 8 ways to get from Erie to Louisville by bus (Flixbus, Greyhound), car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Erie to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Louisvillebus bus Bsb 27 / ...
    10h 13m
    $69–113

  2. Train, bus via Akron

    cheapest
    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Take the bus from W. Prospect Ave & Superior Ave to Robert K Pfaff Transit Center - Akronbus bus 61
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Louisville, KY Bus Stationbus bus
    12h 2m
    $57–137

  3. Drive  442.5 mi

    1. Drive from Erie to Louisvillecar car 442.5 mi
    7h 29m
    $81–117

  4. Fly from Erie International Airport

    1. Fly from Erie International Airport (ERI) to Louisville International Airport (SDF)plane plane ERI - SDF
    7h 22m
    $123–655

  5. Train, bus

    1. Take the train from Erie Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus Greyhound US0135 / ...
    10h 47m
    $98–191

  6. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane plane CLE - SDF
    8h 19m
    $139–761

  7. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Erie, PA to Buffalo, NYbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    8h 35m
    $130–703

  8. Bus to Pittsburgh International Airport, fly

    1. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    8h 40m
    $142–787

Erie to Louisville by bus and foot

Calendar4Weekly Services
Duration10h 13mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Erie to Louisville.ExpandLaunch map view
  • Distance: 458.7 mi
  • Duration: 10h 13m

What companies run services between Erie, PA, USA and Louisville, KY, USA?

You can take a bus from Erie to Louisville via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, and Columbus in around 10h 13m. Alternatively, American Airlines and United Airlines fly from Erie International Airport (ERI) to Louisville International Airport (SDF) 4 times a day.

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