There are 8 ways to get from Erie to Louisville by bus (Flixbus, Greyhound), car, plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Erie to Columbusbus FlixBus 2526
- Take the bus from Columbus to Louisvillebus Bsb 27 / ...
10h 13m$69–113Train, bus via Akron
cheapest- Take the train from Erie Station to Cleveland Amtraktrain
- Take the bus from W. Prospect Ave & Superior Ave to Robert K Pfaff Transit Center - Akronbus 61
- Take the bus from Robert K Pfaff Transit Center - Akron to Louisville, KY Bus Stationbus
12h 2m$57–137Drive 442.5 mi
- Drive from Erie to Louisvillecar 442.5 mi
7h 29m$81–117Fly from Erie International Airport
- Fly from Erie International Airport (ERI) to Louisville International Airport (SDF)plane ERI - SDF
7h 22m$123–655Train, bus
- Take the train from Erie Station to Toledotrain Lake Shore Limited
- Take the bus from Toledo Bus Stop to Louisville Bus Stationbus Greyhound US0135 / ...
10h 47m$98–191Train to Cleveland-Hopkins International Airport, fly
- Take the train from Erie Station to Cleveland Amtraktrain
- Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane CLE - SDF
8h 19m$139–761Bus to Buffalo Niagara International Airport, fly
- Take the bus from Erie, PA to Buffalo, NYbus
- Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane BUF - SDF
8h 35m$130–703Bus to Pittsburgh International Airport, fly
- Take the bus from Erie to Pittsburgh Intermodal Stationbus
- Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane PIT - SDF
8h 40m$142–787
Erie to Louisville by bus and foot
Questions & Answers
The cheapest way to get from Erie to Louisville is to bus which costs $65 - $120 and takes 10h 13m.
The fastest way to get from Erie to Louisville is to fly which takes 7h 22m and costs $120 - $700.
No, there is no direct bus from Erie to Louisville. However, there are services departing from Erie and arriving at Louisville via E Main St & S 5Th St and Columbus. The journey, including transfers, takes approximately 10h 13m.
The distance between Erie and Louisville is 461 miles. The road distance is 445.1 miles.
The best way to get from Erie to Louisville without a car is to bus which takes 10h 13m and costs $65 - $120.
It takes approximately 10h 13m to get from Erie to Louisville, including transfers.
Erie to Louisville bus services, operated by Flixbus USA, depart from Erie station.
The best way to get from Erie to Louisville is to bus which takes 10h 13m and costs $65 - $120. Alternatively, you can fly, which costs $120 - $700 and takes 7h 22m.
Erie to Louisville bus services, operated by Flixbus USA, arrive at Columbus station.
Yes, the driving distance between Erie to Louisville is 445 miles. It takes approximately 7h 29m to drive from Erie to Louisville.
What companies run services between Erie, PA, USA and Louisville, KY, USA?
You can take a bus from Erie to Louisville via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, and Columbus in around 10h 13m. Alternatively, American Airlines and United Airlines fly from Erie International Airport (ERI) to Louisville International Airport (SDF) 4 times a day.
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $160–900
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Sunday
- Estimated price
- $130–800
Flights from Cleveland-Hopkins International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 5h 38m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–800
Flights from Buffalo Niagara International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 59m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 5h 58m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Erie Station to Toledo
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- $50–120
- Website
- Amtrak
Train from Erie Station to Cleveland Amtrak
- Ave. Duration
- 1h 37m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
Train from Erie Station to Cleveland Amtrak
- Ave. Duration
- 1h 37m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Erie to Columbus
- Ave. Duration
- 4h 20m
- Frequency
- 4 times a week
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Erie, PA to Buffalo, NY
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a week
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Erie to Louisville bus tickets online with Omio.
There are 621+ hotels available in Louisville.




