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How to get fromErie to Wythevilleby train, bus, car, plane, bus (Flixbus), or bus (Greyhound)

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There are 8 ways to get from Erie to Wytheville by train, bus, car, plane, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Take the bus from Cleveland to Charlestonbus bus
    3. Take the bus from Charleston to Wythevillebus bus
    12h 22m
    $114–232

  2. Drive  431.3 mi

    cheapest
    1. Drive from Erie to Wythevillecar car 431.3 mi
    7h 21m
    $74–107

  3. Fly Erie International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Erie International Airport (ERI) to Charlotte Douglas International Airport (CLT)plane plane ERI - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 58m
    $155–643

  4. Bus

    1. Take the bus from Erie to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Wythevillebus bus Bsb 32
    13h 12m
    $94–169

  5. Bus via Brook Park (Greyhound)

    1. Take the bus from Erie to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Columbusbus bus
    3. Take the bus from Columbus to Max Meadowsbus bus
    14h 24m
    $139–210

  6. Fly Erie International Airport to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Erie International Airport (ERI) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane ERI - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    10h 16m
    $90–411

  7. Train to Cleveland-Hopkins International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the train from Erie Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Charlotte Douglas International Airport (CLT)plane plane CLE - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    9h 20m
    $228–924

  8. Bus to Buffalo Niagara International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Erie to Buffalobus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    10h 2m
    $173–693

Erie International Airport (ERI) to Charlotte Douglas International Airport (CLT) flights

Calendar17Weekly Planes
Duration2h 11mAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Erie to Wytheville.ExpandLaunch map view
  • Distance: 499.3 mi
  • Duration: 12h 22m

What companies run services between Erie, PA, USA and Wytheville, VA, USA?

You can take a bus from Erie to Wytheville via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, and Wytheville in around 13h 12m.

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