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How to get fromEstación Sur de Autobuses to Brusselsby plane, train (Renfe, Ouigo, TGV, Eurostar), bus, car, or train

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There are 8 ways to get from Estación Sur de Autobuses to Brussels by plane, train (Renfe, Ouigo, TGV, Eurostar), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Brussels Airport

    best
    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brussels Airport (BRU)plane plane MAD - BRU
    5h 9m
    €64–210

  2. Train

    1. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    2. Take the train from Barcelona-Sants to Paris Gare De Lyontrain train Tgv
    3. Take the train from Paris Nord to Brussel-Zuid / Bruxelles-Miditrain train
    13h 12m
    €326–682

  3. Bus

    1. Take the bus from Estación Sur de Autobuses to Paris - Bercy-Seine Bus Stationbus bus BlaBlaCar Bus
    2. Take the bus from Paris - Bercy-Seine Bus Station to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    19h 33m
    €135–244

  4. Drive 1,542.7 km

    1. Drive from Estación Sur de Autobuses to Brusselscar car 1,542.7 km
    15h 19m
    €242–349

  5. Fly to Brussels South Charleroi Airport, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brussels South Charleroi Airport (CRL)plane plane MAD - CRL
    2. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    6h 38m
    €79–308

  6. Fly to Amsterdam Airport Schiphol, train

    1. Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Amsterdam Airport Schiphol (AMS)plane plane MAD - AMS
    2. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    7h 8m
    €132–345

  7. Bus via Paris

    1. Take the bus from Estación Sur de Autobuses to Paris, Quai de Bercybus bus
    2. Take the bus from Paris - Bercy-Seine Bus Station to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    19h 33m
    €72–200

  8. Bus #2

    1. Take the bus from Madrid to Brussels-North train stationbus bus FlixBus N1143
    22h 35m
    €130–230

Estación Sur de Autobuses to Brussels by train

Calendar32Weekly Trains
Duration13h 12mAverage Duration
Ticket€326Cheapest Price
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Questions & Answers

Map of how to get from Estación Sur de Autobuses to Brussels.ExpandLaunch map view
  • Distance: 1,348.5 km
  • Duration: 5h 9m

What companies run services between Estación Sur de Autobuses, Spain and Brussels, Belgium?

Iberia, Ryanair, and three other airlines fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brussels Airport (BRU) every 3 hours. Alternatively, you can take a train from Méndez Álvaro P.V. to Brussel-Zuid / Bruxelles-Midi via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Paris Gare de Lyon, and Paris Nord in around 13h 12m.

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