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How to get fromEstero to Destinby plane, bus, taxi, or car

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There are 10 ways to get from Estero to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Destin–Fort Walton Beach Airport

    best
    1. Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane plane RSW - VPS
    7h 21m
    $128–530

  2. Drive  507.4 mi

    cheapest
    1. Drive from Estero to Destincar car 507.4 mi
    10h 10m
    $93–134

  3. Bus, taxi

    1. Take the bus from Fort Myers 7-11 to Tallahassee, FLbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    22h 16m
    $296–413

  4. Fly Ft. Myers to Northwest Florida Beaches International Airport, taxi

    1. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    8h 30m
    $228–655

  5. Fly Ft. Myers to Pensacola International Airport, taxi

    1. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    8h 21m
    $194–545

  6. Bus to Miami International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    8h 40m
    $120–436

  7. Bus to Miami International Airport, fly to Pensacola International Airport, taxi

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    9h 33m
    $190–481

  8. Bus to Tampa, fly to Pensacola International Airport, taxi

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane plane TPA - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    10h 34m
    $354–629

  9. Bus, taxi via Sandy Springs

    1. Take the bus from Fort Myers 7-11 to University of Florida - 1956 Gale Lemerand Drbus bus
    2. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    23h 38m
    $359–489

  10. Drive, bus, taxi

    1. Drive from Estero to Clewistoncar car
    2. Take the bus from Clewiston to West Palm Beach Bus Stationbus bus
    3. Take the bus from West Palm Beach Bus Station to Jacksonvillebus bus
    4. Take the bus from Jacksonville to Mobile Bus Stationbus bus
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    28h 55m
    $264–396

Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar55Weekly Planes
Duration5h 21mAverage Duration
Ticket$87Cheapest Price
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Comparing Your Travel Options

Map of how to get from Estero to Destin.ExpandLaunch map view
  • Distance: 436.5 mi
  • Duration: 7h 21m

What companies run services between Estero, FL, USA and Destin, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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