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How to get fromEstero to Jacksonvilleby bus (Flixbus), bus, train, car, or plane

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There are 7 ways to get from Estero to Jacksonville by bus (Flixbus), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus FlixBus 2433 / ...
    11h 13m
    $54–91

  2. Bus via Tampa (Flixbus)

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    3. Take the bus from Gainesville to Jacksonvillebus bus
    11h 22m
    $52–87

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Jacksonvilletrain train Floridian
    13h 8m
    $88–188

  4. Drive  305.4 mi

    1. Drive from Estero to Jacksonvillecar car 305.4 mi
    5h 39m
    $56–81

  5. Fly from Ft. Myers

    1. Fly from Ft. Myers (RSW) to Jacksonville (JAX)plane plane RSW - JAX
    8h 25m
    $294–758

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane plane FLL - JAX
    8h 33m
    $134–409

  7. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    9h 21m
    $82–399

Estero to Jacksonville by bus (Flixbus)

Calendar20Weekly Buses
Duration11h 13mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

Map of how to get from Estero to Jacksonville.ExpandLaunch map view
  • Distance: 378.5 mi
  • Duration: 11h 13m

What companies run services between Estero, FL, USA and Jacksonville, FL, USA?

You can take a bus from S Tamiami Trl @ County Rd to Jacksonville via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, and Orlando Bus Station in around 11h 13m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Ft. Myers (RSW) to Jacksonville (JAX) every 2 hours.

Airlines
Train operators
Bus operators

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