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How to get fromEstero to Myrtle Beachby plane, bus, train, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Estero to Myrtle Beach by plane, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Myrtle Beach

    best
    1. Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane plane RSW - MYR
    7h 5m
    $354–619

  2. Bus to Tampa, fly to Myrtle Beach

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    8h 50m
    $114–608

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    21h 27m
    $184–378

  4. Drive 636.5 mi

    1. Drive from Estero to Myrtle Beachcar car 636.5 mi
    11h 51m
    $117–168

  5. Fly Ft. Myers to Wilmington International Airport, bus

    1. Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)plane plane RSW - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 39m
    $260–596

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane plane FLL - MYR
    7h 34m
    $164–515

  7. Bus to Orlando, fly to Myrtle Beach

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Fly from Orlando (MCO) to Myrtle Beach (MYR)plane plane MCO - MYR
    11h 10m
    $140–402

  8. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Camdenbus bus
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    23h 18m
    $122–251

Estero to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration21h 27mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

Map of how to get from Estero to Myrtle Beach.ExpandLaunch map view
  • Distance: 545.8 mi
  • Duration: 7h 5m

What companies run services between Estero, FL, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from S Tamiami Trl @ County Rd to Myrtle Beach Bus Station via South Fort Myers Transfer/P&R, Fort Myers Bus Stop, Orlando Bus Station, Jacksonville, and Camden in around 23h 18m.

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