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How to get fromEstero to Panama City Beachby plane, bus (Flixbus, Greyhound), or car

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There are 5 ways to get from Estero to Panama City Beach by plane, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    7h 19m
    $144–550

  2. Bus

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    15h 16m
    $84–158

  3. Bus via Gainesville

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    12h 39m
    $154–250

  4. Drive 468.7 mi

    1. Drive from Estero to Panama City Beachcar car 468.7 mi
    9h 23m
    $86–124

  5. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane plane RSW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    8h 17m
    $108–501

Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP) flights

Calendar64Weekly Planes
Duration5h 33mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Estero to Panama City Beach.ExpandLaunch map view
  • Distance: 400.2 mi
  • Duration: 7h 19m

What companies run services between Estero, FL, USA and Panama City Beach, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP) every 3 hours. Alternatively, you can take a vehicle from Estero to Panama City Beach via Fort Myers 7-11, University of South Florida, Gainesville, Tallahassee, and Panama City Beach Bus Station in around 12h 39m.

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