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How to get fromEugene to Knoxvilleby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Eugene to Knoxville by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mahlon Sweet Field Airport to Mcghee Tyson Airport

    best
    1. Fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS)plane plane EUG - TYS
    7h 45m
    $336–1,176

  2. Fly Mahlon Sweet Field Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Mahlon Sweet Field Airport (EUG) to Asheville Regional Airport (AVL)plane plane EUG - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    10h 1m
    $183–691

  3. Train, bus

    1. Take the train from Eugene to Portlandtrain train
    2. Take the train from Portland to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 12h
    $1,188–2,394

  4. Bus

    1. Take the bus from Eugene to Sacramento Bus Stationbus bus
    2. Take the bus from Sacramento Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    5. Take the bus from New York to Knoxvillebus bus
    4d 2h
    $812–1,443

  5. Drive 2,501.2 mi

    1. Drive from Eugene to Knoxvillecar car 2,501.2 mi
    42h 29m
    $457–660

  6. Bus to Roberts Field-Redmond Municipal Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Eugene Amtrak Bus Platform to Redmond Airportbus bus
    2. Fly from Roberts Field-Redmond Municipal Airport (RDM) to Mcghee Tyson Airport (TYS)plane plane RDM - TYS
    10h 58m
    $310–1,116

  7. Train to Portland International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Eugene to Portlandtrain train
    2. Fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS)plane plane PDX - TYS
    11h 18m
    $388–1,354

  8. Bus, train

    1. Take the bus from Eugene Amtrak Station Bus Platform to Portland Amtrak Stationbus bus
    2. Take the bus from Portland Curbside Bus Stop to Vancouverbus bus
    3. Take the train from Vancouver to Toronto Union Stationtrain train
    4. Take the train from Toronto Union Station to New York Penn Stationtrain train
    5. Take the bus from New York to Knoxvillebus bus
    5d 12h
    $1,090–2,203

Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS) flights

Calendar34Weekly Planes
Duration6h 59mAverage Duration
Ticket$285Cheapest Price
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Questions & Answers

Map of how to get from Eugene to Knoxville.ExpandLaunch map view
  • Distance: 2,154.8 mi
  • Duration: 7h 45m

What companies run services between Eugene, OR, USA and Knoxville, TN, USA?

Southwest Airlines and United Airlines fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS) 5 times a day. Alternatively, you can take a bus from Eugene to Knoxville via Sacramento Bus Station, Los Angeles Union Station, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 4d 2h.

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