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How to get fromEugene to Knoxvilleby plane, train, bus, bus (Flixbus, Greyhound), or car

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There are 8 ways to get from Eugene to Knoxville by plane, train, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mahlon Sweet Field Airport to Mcghee Tyson Airport

    best
    1. Fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS)plane plane EUG - TYS
    7h 39m
    $316–1,276

  2. Fly Mahlon Sweet Field Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Mahlon Sweet Field Airport (EUG) to Asheville Regional Airport (AVL)plane plane EUG - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    10h 1m
    $143–591

  3. Train, bus

    1. Take the train from Eugene to Portlandtrain train
    2. Take the train from Portland to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 12h
    $948–2,235

  4. Bus

    1. Take the bus from Eugene to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to New York Midtownbus bus
    5. Take the bus from New York to Knoxvillebus bus
    3d 15h
    $713–1,087

  5. Drive  2,501.2 mi

    1. Drive from Eugene to Knoxvillecar car 2,501.2 mi
    42h 29m
    $457–660

  6. Bus to Roberts Field-Redmond Municipal Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Eugene Amtrak Bus Platform to Redmond Airportbus bus
    2. Fly from Roberts Field-Redmond Municipal Airport (RDM) to Mcghee Tyson Airport (TYS)plane plane RDM - TYS
    11h 25m
    $309–1,216

  7. Train to Portland International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Eugene to Portlandtrain train
    2. Fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS)plane plane PDX - TYS
    11h 2m
    $358–1,345

  8. Bus, train

    1. Take the bus from Eugene Amtrak Station Bus Platform to Portland Amtrak Stationbus bus
    2. Take the train from Portland to Vancouvertrain train
    3. Take the train from Vancouver to Toronto Union Stationtrain train
    4. Take the train from Toronto Union Station to New York Penn Stationtrain train
    5. Take the bus from New York to Knoxvillebus bus
    5d 12h
    $1,120–2,318

Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS) flights

Calendar22Weekly Planes
Duration7h 2mAverage Duration
Ticket$269Cheapest Price
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Comparing Your Travel Options

Map of how to get from Eugene to Knoxville.ExpandLaunch map view
  • Distance: 2,154.8 mi
  • Duration: 7h 39m

What companies run services between Eugene, OR, USA and Knoxville, TN, USA?

Southwest Airlines, United Airlines, and Allegiant Air fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS) 3 times a day. Alternatively, you can take a bus from Eugene to Knoxville via Pasco Bus Stop, Denver Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 3d 15h.

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