What is the cheapest way to get from Florence to Isernia?

The cheapest way to get from Florence to Isernia is to bus via Rome which costs €25 - €70 and takes 6h 25m.

What is the fastest way to get from Florence to Isernia?

The fastest way to get from Florence to Isernia is to drive which takes 4h 6m and costs €65 - €100.

Is there a direct bus between Florence and Isernia?

Yes, there is a direct bus departing from Florence Villa Constanza Bus Station station and arriving at Isernia. Services depart once daily, and operate every day. The journey takes approximately 9h 54m.

Is there a direct train between Florence and Isernia?

No, there is no direct train from Florence to Isernia. However, there are services departing from Firenze Santa Maria Novella and arriving at Isernia via Roma Tiburtina. The journey, including transfers, takes approximately 4h 40m.

How far is it from Florence to Isernia?

The distance between Florence and Isernia is 441 km. The road distance is 428.2 km.

How do I travel from Florence to Isernia without a car?

The best way to get from Florence to Isernia without a car is to train which takes 4h 40m and costs €55 - €110.

How long does it take to get from Florence to Isernia?

It takes approximately 4h 40m to get from Florence to Isernia, including transfers.

Where do I catch the Florence to Isernia bus from?

Florence to Isernia bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.

Where do I catch the Florence to Isernia train from?

Florence to Isernia train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.

Train or bus from Florence to Isernia?

The best way to get from Florence to Isernia is to train which takes 4h 40m and costs €55 - €110. Alternatively, you can bus via Rome, which costs €25 - €70 and takes 6h 25m.

Where does the Florence to Isernia bus arrive?

Florence to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.

Where does the Florence to Isernia train arrive?

Florence to Isernia train services, operated by ItaloTreno, arrive at Roma Tiburtina station.

Can I drive from Florence to Isernia?

Yes, the driving distance between Florence to Isernia is 428 km. It takes approximately 4h 6m to drive from Florence to Isernia.

How do I get a train ticket from Florence to Isernia?

Book your Florence to Isernia train tickets online with Omio.

How do I get a bus ticket from Florence to Isernia?

Book your Florence to Isernia bus tickets online with Omio and FlixBus.

Where can I stay near Isernia?

There are 454+ hotels available in Isernia.

Florence to Isernia - 8 ways to travel via train, bus, car, and plane

How to get fromFlorence to Isernia

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There are 8 ways to get from Florence to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train
best
1. Take the train from Firenze Santa Maria Novella to Roma Tiburtinatrain 8902 / ...
2. Take the train from Roma Tiburtina to Iserniatrain Re
4h 40m
€55–103
Bus via Rome
cheapest
1. Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...
2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
6h 25m
€25–67
Drive 428.2 km
1. Drive from Florence to Iserniacar 428.2 km
4h 6m
€68–98
Fly to Fiumicino International Airport, train
1. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
2. Take the train from Roma Termini to Iserniatrain
6h 1m
€88–229
Train via Rome (Trenitalia)
1. Take the train from Firenze S.M.N. to Roma Terminitrain Fr
2. Take the train from Roma Termini to Iserniatrain Re
4h 52m
€51–115
Bus, train
1. Take the bus from Florence to Cassino Bar Varlesebus
2. Take the train from Cassino to Iserniatrain Re
7h 21m
€33–48
Bus
1. Take the bus from Florence Villa Constanza Bus Station to Iserniabus 433
9h 54m
€50–90
Fly to Naples Airport, train
1. Fly from Florence Peretola Airport (FLR) to Naples Airport (NAP)plane FLR - NAP
2. Take the train from Caserta to Iserniatrain
7h 55m
€100–225

Florence to Isernia by bus

27Weekly Buses

6h 25mAverage Duration

€25Cheapest Price

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Questions & Answers

Map of how to get from Florence to Isernia.

Launch map view

Distance: 441.4 km
Duration: 4h 40m

What companies run services between Florence, Italy and Isernia, Italy?

You can take a train from Firenze Santa Maria Novella to Isernia via Roma Tiburtina in around 4h 40m. Alternatively, you can take a bus from Florence Villa Constanza Bus Station to Isernia via Roma, Autostazione Tiburtina in around 6h 25m.

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