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How to get fromFlorence to Mainzby plane, train (Trenitalia), bus, car, or train

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There are 10 ways to get from Florence to Mainz by plane, train (Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Florence Peretola Airport

    best
    1. Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane plane FLR - FRA
    4h 32m
    €126–285

  2. Bus via Frankfurt am Main

    cheapest
    1. Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationbus bus N77 / ...
    18h 23m
    €90–149

  3. Train via Basel

    1. Take the train from Firenze Santa Maria Novella to Milano Rogoredotrain train
    2. Take the train from Rho-Fiera Milano to Basel Sbbtrain train Ec
    3. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    11h 11m
    €172–435

  4. Bus

    1. Take the bus from Florence Villa Constanza Bus Station to Wiesbaden Gartenfeldstraße P+Rbus bus
    16h 50m
    €135–197

  5. Drive  958.6 km

    1. Drive from Florence to Mainzcar car 958.6 km
    9h 2m
    €151–219

  6. Train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    2. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane plane BLQ - FRA
    4h 58m
    €114–322

  7. Train to Pisa International Airport, fly

    1. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    2. Fly from Pisa International Airport (PSA) to Frankfurt (FRA)plane plane PSA - FRA
    5h 45m
    €119–275

  8. Train to Verona Villafranca Airport, fly

    1. Take the train from Firenze S.M.N. to Verona Porta Nuovatrain train
    2. Fly from Verona Villafranca Airport (VRN) to Frankfurt (FRA)plane plane VRN - FRA
    6h
    €150–348

  9. Train to Venice Marco Polo Airport, fly

    1. Take the train from Firenze S.M.N. to Venezia Mestretrain train
    2. Fly from Venice Marco Polo Airport (VCE) to Frankfurt (FRA)plane plane VCE - FRA
    6h 29m
    €115–273

  10. Train

    1. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    11h 23m
    €164–285

Florence to Mainz by train

Calendar7Weekly Trains
Duration11h 23mAverage Duration
Ticket€164Cheapest Price
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Questions & Answers

Map of how to get from Florence to Mainz.ExpandLaunch map view
  • Distance: 753.8 km
  • Duration: 4h 32m

What companies run services between Florence, Italy and Mainz, Germany?

Lufthansa, Air Dolomiti, and Swiss fly from Florence Peretola Airport (FLR) to Frankfurt (FRA) every 3 hours. Alternatively, you can take a train from Firenze Santa Maria Novella to Mainz, Hauptbahnhof via Rho-Fiera Milano, Basel SBB, and Mannheim, Hauptbahnhof in around 11h 11m.

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