There are 6 ways to get from Florence to Mendrisio by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain Re80
3h 30mCHF 50–147Bus
- Take the bus from Florence Villa Constanza Bus Station to Comobus
5h 31mDrive 355.1 km
- Drive from Florence to Mendrisiocar 355.1 km
3h 35mCHF 59–85Fly to Milano Malpensa Airport, train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 51mCHF 91–247Train via Firenze Santa Maria Novella
- Take the train from Firenze Santa Maria Novella to Milano Centraletrain 8134 / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
4h 7mCHF 56–136Fly to Milan Linate Airport, train
- Fly from Florence Peretola Airport (FLR) to Milan Linate Airport (LIN)plane FLR - LIN
- Take the train from Monza to Mendrisiotrain
6h 2mCHF 107–261
Florence to Mendrisio by train
Questions & Answers
The cheapest way to get from Florence to Mendrisio is to train via Firenze Santa Maria Novella which costs SFr 55 - SFr 140 and takes 4h 7m.
The fastest way to get from Florence to Mendrisio is to train which takes 3h 30m and costs SFr 50 - SFr 150.
No, there is no direct bus from Florence to Mendrisio. However, there are services departing from Florence and arriving at Mendrisio, Autosilo via Florence Villa Constanza Bus Station, Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 5h 31m.
No, there is no direct train from Florence to Mendrisio. However, there are services departing from Firenze S.M.N. and arriving at Mendrisio via Milano Centrale. The journey, including transfers, takes approximately 3h 30m.
The distance between Florence and Mendrisio is 363 km. The road distance is 355.1 km.
The best way to get from Florence to Mendrisio without a car is to train which takes 3h 30m and costs SFr 50 - SFr 150.
It takes approximately 3h 30m to get from Florence to Mendrisio, including transfers.
Florence to Mendrisio bus services, operated by Onebus, depart from Florence Villa Constanza Bus Station.
Florence to Mendrisio train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Mendrisio is to train which takes 3h 30m and costs SFr 50 - SFr 150. Alternatively, you can bus, which costs and takes 5h 31m.
What companies run services between Florence, Italy and Mendrisio, Switzerland?
You can take a train from Firenze S.M.N. to Mendrisio via Milano Centrale in around 3h 30m. Alternatively, Onebus operates a bus from Florence Villa Constanza Bus Station to Como once a week, and the journey takes 3h 7m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- CHF 80–280
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- CHF 140–600
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- CHF 130–240
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- CHF 170–750
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- CHF 110–950
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 100–370
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- CHF 140–600
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- CHF 170–750
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- CHF 130–240
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- CHF 110–950
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- CHF 140–600
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Saturday
- Estimated price
- CHF 170–750
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- CHF 210–950
- Website
- flexflight.dk
Flights from Florence Peretola Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 2h 30m
- When
- Friday
- Estimated price
- CHF 40–550
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 4h 20m
- When
- Monday and Friday
- Estimated price
- CHF 120–750
- Website
- swiss.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- CHF 80–280
- Website
- polarair.ru
Flights from Florence Peretola Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 2h 30m
- When
- Friday
- Estimated price
- CHF 40–550
- Website
- aeroitalia.com
Flights from Florence Peretola Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 4h 20m
- When
- Monday and Friday
- Estimated price
- CHF 120–750
- Website
- easyjet.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Olbia
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- CHF 50–220
- Website
- austrian.com
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 100–370
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 56m
- Frequency
- Hourly
- Estimated price
- CHF 40–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- CHF 35–75
- Website
- https://www.italotreno.it/en
Train from Firenze Santa Maria Novella to Milano Centrale
- Ave. Duration
- 2h 33m
- Frequency
- Hourly
- Estimated price
- CHF 35–75
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- CHF 30–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–65
- Website
- https://www.sbb.ch/en
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 20–65
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–65
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Florence Villa Constanza Bus Station to Como
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Website
- https://onebus.it/
Want to know more about travelling around Switzerland
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More Questions & Answers
Florence to Mendrisio bus services, operated by Onebus, arrive at Como station.
Florence to Mendrisio train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
Yes, the driving distance between Florence to Mendrisio is 355 km. It takes approximately 3h 35m to drive from Florence to Mendrisio.
There are 5868+ hotels available in Mendrisio.






















