There are 7 ways to get from Florence to Mendrisio by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Firenze Santa Maria Novella to Milano Centraletrain 8134 / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
3h 29mCHF 56–85Bus
cheapest- Take the bus from Florence Villa Constanza Bus Station to Comobus 518
6h 17mCHF 32–50Bus via Batoni
- Take the bus from Florence Villa Constanza Bus Station to Comobus
5h 20mCHF 60–88Drive 355.1 km
- Drive from Florence to Mendrisiocar 355.1 km
3h 36mCHF 60–86Fly to Milano Malpensa Airport, train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 51mCHF 91–241Train #2
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain Re80
3h 29mCHF 52–97Fly to Milan Linate Airport, train
- Fly from Florence Peretola Airport (FLR) to Milan Linate Airport (LIN)plane FLR - LIN
- Take the train from Monza to Mendrisiotrain
6h 42mCHF 107–221
Florence to Mendrisio by train
Questions & Answers
The cheapest way to get from Florence to Mendrisio is to bus which costs SFr 30 - SFr 50 and takes 6h 17m.
The fastest way to get from Florence to Mendrisio is to train which takes 3h 29m and costs SFr 55 - SFr 85.
No, there is no direct bus from Florence station to Mendrisio. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Mendrisio, Autosilo via Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 5h 20m.
No, there is no direct train from Florence to Mendrisio. However, there are services departing from Firenze Santa Maria Novella and arriving at Mendrisio via Milano Centrale. The journey, including transfers, takes approximately 3h 29m.
The distance between Florence and Mendrisio is 362 km. The road distance is 355.1 km.
The best way to get from Florence to Mendrisio without a car is to train which takes 3h 29m and costs SFr 55 - SFr 85.
It takes approximately 3h 29m to get from Florence to Mendrisio, including transfers.
Florence to Mendrisio bus services, operated by Onebus, depart from Florence Villa Constanza Bus Station.
Florence to Mendrisio train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
The best way to get from Florence to Mendrisio is to train which takes 3h 29m and costs SFr 55 - SFr 85. Alternatively, you can bus via Batoni, which costs SFr 55 - SFr 90 and takes 5h 20m.
What companies run services between Florence, Italy and Mendrisio, Switzerland?
You can take a train from Firenze Santa Maria Novella to Mendrisio via Milano Centrale in around 3h 29m. Alternatively, Onebus operates a bus from Florence Villa Constanza Bus Station to Como once a week. Tickets cost CHF 55–80 and the journey takes 3h 7m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- CHF 75–280
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- CHF 140–490
Flights from Florence Peretola Airport to Milan Linate Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- CHF 130–210
Flights from Florence Peretola Airport to Milan Linate Airport via Munich
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- CHF 170–600
Flights from Florence Peretola Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- CHF 100–650
Flights from Florence Peretola Airport to Milan Linate Airport via Vienna
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- CHF 95–360
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 30–60
- Website
- Italo Treno
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- CHF 30–60
- Website
- Italo Treno
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Florence Villa Constanza Bus Station to Como
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Estimated price
- CHF 55–80
- Website
- Onebus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Florence to Mendrisio bus services, operated by Onebus, arrive at Como station.
Florence to Mendrisio train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Florence to Mendrisio is 355 km. It takes approximately 3h 36m to drive from Florence to Mendrisio.
There are 5736+ hotels available in Mendrisio.