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How to get fromFlorence to Mendrisioby train, bus, car, plane, or train (Trenitalia)

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There are 7 ways to get from Florence to Mendrisio by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Firenze Santa Maria Novella to Milano Centraletrain train 8134 / ...
    2. Take the train from Milano Centrale to Mendrisiotrain train Re80
    3h 29m
    CHF 52–80

  2. Bus

    cheapest
    1. Take the bus from Florence Villa Constanza Bus Station to Comobus bus 518
    6h 7m
    CHF 32–50

  3. Bus via Batoni

    1. Take the bus from Florence Villa Constanza Bus Station to Comobus bus
    5h 16m
    CHF 60–88

  4. Drive  355.1 km

    1. Drive from Florence to Mendrisiocar car 355.1 km
    3h 36m
    CHF 59–86

  5. Fly to Milano Malpensa Airport, train

    1. Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane plane FLR - MXP
    2. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    5h 51m
    CHF 116–258

  6. Train #2

    1. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    2. Take the train from Milano Centrale to Mendrisiotrain train Re80
    3h 29m
    CHF 49–92

  7. Fly to Milan Linate Airport, train

    1. Fly from Florence Peretola Airport (FLR) to Milan Linate Airport (LIN)plane plane FLR - LIN
    2. Take the train from Monza to Mendrisiotrain train
    6h 42m
    CHF 117–221

Florence to Mendrisio by train

Calendar137Weekly Trains
Duration3h 29mAverage Duration
TicketCHF 49Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florence to Mendrisio.ExpandLaunch map view
  • Distance: 362 km
  • Duration: 3h 29m

What companies run services between Florence, Italy and Mendrisio, Switzerland?

You can take a train from Firenze Santa Maria Novella to Mendrisio via Milano Centrale in around 3h 29m. Alternatively, Onebus operates a bus from Florence Villa Constanza Bus Station to Como once a week. Tickets cost CHF 55–80 and the journey takes 3h 7m.

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